{"_buckets": {"deposit": "814e5bbe-40c6-4673-a06e-6273204f8b29"}, "_deposit": {"id": "10593", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10593"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00010593", "sets": ["456", "975"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Inducibility of Atrial Fibrillation in Myocarditis Depends not on Inflammation but on Atrial Structural Remodeling"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "9", "bibliographicPageEnd": "454", "bibliographicPageStart": "442", "bibliographicVolumeNumber": "123", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "背景 : 炎症と心房細動の関連を支持する報告が増えてきている. しかし, 心房細動発症における炎症の直接的な役割については不明な点が多い. 方法・結果 : 自己免疫性心筋炎 (EAM) 感作14日目 (n =7) および56日目 (n =7) のラットに対し, 経頚静脈的に電極カテーテルを右心房へ挿入し, 心房頻回刺激による心房細動の誘発を試みた. EAM感作14日目では心房細動は誘発されなかった. EAM感作56日目のラットでは心房細動が誘発され (15匹中11匹), 心房の著明な線維化と心筋細胞の肥大を伴っていた. さらに, EAM感作28日目から55日目にかけてアンギオテンシンIIタイプI受容体遮断薬 (ARB) を投与したところ, 心房細動は誘発されなくなり (8匹中0匹), 心房における間質の線維化と心筋細胞肥大は改善を認めた. 結論 : 心筋炎急性期には心房細動は誘発されなかった. 心房の器質的リモデリングを認めた心筋炎慢性期では心房細動が誘発され, ARBの使用によって心房の器質的リモデリング, 心房細動の誘発はともに抑制された. 炎症後心不全に伴う器質的リモデリングが, 心房細動発症に重要な役割を果たしていると考えられた.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "72438", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Hoyano, Makoto"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "保屋野, 真"}], "nameIdentifiers": [{"nameIdentifier": "72437", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "123(9)_442-454.pdf", "filesize": [{"value": "2.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2200000.0, "url": {"label": "123(9)_442-454.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/10593/files/123(9)_442-454.pdf"}, "version_id": "6d23fbc6-b6e8-43ce-8fd0-f4371ddc235d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "心房細動", "subitem_subject_scheme": "Other"}, {"subitem_subject": "炎症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "心房リモデリング", "subitem_subject_scheme": "Other"}, {"subitem_subject": "アンギオテンシンIIタイプⅠ受容体遮断薬", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "心房細動誘発における炎症の役割についての実験的検討", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "心房細動誘発における炎症の役割についての実験的検討"}, {"subitem_title": "心房細動誘発における炎症の役割についての実験的検討", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "975"], "permalink_uri": "http://hdl.handle.net/10191/28507", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-07-22"}, "publish_date": "2014-07-22", "publish_status": "0", "recid": "10593", "relation": {}, "relation_version_is_last": true, "title": ["心房細動誘発における炎症の役割についての実験的検討"], "weko_shared_id": null}