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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.48 No.3

Multiple Drug Resistance of Vibrio cholerae O1 and O139 Isolated from Various Regions of the World: Changes in the Past 10 Years

http://hdl.handle.net/10191/1849
http://hdl.handle.net/10191/1849
d0d87695-60a1-4a9c-96fa-73e565fba48e
名前 / ファイル ライセンス アクション
KJ00000007261.pdf KJ00000007261.pdf (3.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-05-10
タイトル
タイトル Multiple Drug Resistance of Vibrio cholerae O1 and O139 Isolated from Various Regions of the World: Changes in the Past 10 Years
タイトル
タイトル Multiple Drug Resistance of Vibrio cholerae O1 and O139 Isolated from Various Regions of the World: Changes in the Past 10 Years
言語 en
言語
言語 eng
キーワード
主題Scheme Other
主題 multiple drug resistance
キーワード
主題Scheme Other
主題 Vibrio cholerae O1
キーワード
主題Scheme Other
主題 Vibrio cholerae O139
キーワード
主題Scheme Other
主題 VC MAR pattern
キーワード
主題Scheme Other
主題 R plasmid
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 YAMAMOTO, Tatsuo

× YAMAMOTO, Tatsuo

WEKO 52339

YAMAMOTO, Tatsuo

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TANEIKE, Ikue

× TANEIKE, Ikue

WEKO 52340

TANEIKE, Ikue

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TAMURA, Yukiko

× TAMURA, Yukiko

WEKO 52341

TAMURA, Yukiko

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WAKISAKA-SAITO, Noriko

× WAKISAKA-SAITO, Noriko

WEKO 52342

WAKISAKA-SAITO, Noriko

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抄録
内容記述タイプ Abstract
内容記述 In vitro susceptibilities to 35 antimicrobial agents were investigated in 319 strains of Vibrio cholerae O1 and 213 strains of V. cholerae O139 isolated from various regions of the world between 1991 and 1999. Drug resistance was found with 12 of the 35 antimicrobial agents and was divided into chromosome-encoded multiple drug resistance (VC MAR, found in plasmid-less strains) and that encoded by drug resistance (R) plasmids. VC MAR was subtyped into eight major groups. In Bangladesh, the VC MAR pattern changed from that including tetracycline resistance (VC MAR2) since the 1990s to a tetracycline-susceptible, nalidixic acid-low resistant pattern (VC MAR3a), and then to a nalidixic acid-highly resistant pattern (VC MAR3b). The VC MAR3b type also showed low resistance to a newer quinolone, norfloxacin. R plasmids were isolated from a V. cholerae O139 strain from Thailand and V. cholerae O1 strains from Rwanda, Tanzania, and Peru. In the case of V. cholerae O139,this was the second isolate after the previous R plasmid from Indian strains. V. cholerae O1 isolated in 1997 from cholera patients in Japan who had never been abroad showed a VC MAR6 pattern, which was the same as that of V. cholerae O1 occurring in travelers to Bali, Indonesia in 1995. This study showed that the multiple drug resistance of V. cholerae O1 and O139 differed among regions and eras due to changes in VC MAR and the presence of R plasmids, and that the isolates were still susceptible to some antimicrobial agents such as azithromycin and tetracycline (e.g., in Bangladesh).
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 48, 号 3, p. 75-88, 発行日 2000-09
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
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