@article{oai:niigata-u.repo.nii.ac.jp:00009736,
 author = {平山, 匡男 and 西田, 浩志 and 渡辺, 賢一 and 荒木, 善紀 and 後藤, 博 and 古内, 亮 and 坂口, 良子},
 issue = {4},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Apr},
 note = {【目的】ラジウム温泉に入浴した時の上腕動脈血管内皮機能, 生理学的検査値および自覚的体感の変動を, 入浴中および入浴終了後2時間まで測定し, 入浴がこれらに及ぼす影響を評価することを目的とした. 【方法と対象】健常成人16名 (男女それぞれ8名) がラジウム温泉に20分間入浴中および入浴終了後2時間までの間, 血管内皮機能検査 [血流依存性血管拡張反応率, flow-mediated dilation (FMD%) と血管拡張径増加量], 生理学的検査 (血圧, 脈拍, 体温, 体重, 体脂肪率), 自覚的体感 (快適感, リラックス感, 体のすっきり感) の測定を行い, その変動を解析した. 【結果】ラジウム温泉入浴中のFMD%および血管拡張径増加量のそれぞれの平均値は, 入浴前 (7.5±0.8%および0.27±0.03mm) から入浴終了直後 (9.3士1.0%および0.35±0.03mm) に有意に上昇し, 入浴終了2時間後 (9.0±1.%および0.31±0.03mm) も有意な上昇は保持された. この変動を男女別に解析すると, 女性群でのみ入浴終了後2時間まで有意な上昇が確認された. 収縮期および拡張期血圧, 体重, 体脂肪率も入浴中および入浴終了後2時間ほでそれぞれ有意な低下が認められたが, 体温および脈拍の上昇は入浴中のみであった. VAS法で測定した快適感, リラックス感, 体のすっきり感の自覚的体感は入浴中, 入浴終了2時間後ともにそれぞれ有意な改善が認められた. 【総括】ラジウム温泉浴が及ぼす生理的作用について, 上腕動脈血管内皮機能の検査を組み入れて評価した結果, 入浴中および入浴後の血流依存性血管拡張反応率 (FMD%) と血管拡張径を増加させる効果があることを見出し, かつ血圧の低下や自覚的体感も向上させる利点もあることを明らかにした., Effects of radium hot spring bathing on flow-mediated dilation, physiologic values, and subjective feeling were investigated in healthy adults. Sixteen adults (8 men and 8 women) were subjected to bathing for 20 min and staying in rest until 2 h postbathing. During the period of bathing and postbathing, effects on brachial artery flow-mediated dilation (FMD and vascular diameter), physiologic values, and subjective feeling were measured and analyzed. Average values of FMD and vascular diameter, 7.5±0.8% and 0.27±0.03mm, before bathing increased significantly to 9.3±1.0% and 0.35±0.03mm during 20 min bathing and then these significant increases were sustained for 2 h after bathing, respectively. Subgroup analysis of these changes for men and women revealed that significant increases after bathing were sustained only in a women’s group. The average values of systolic and diastolic blood pressures, body weights, and body fat percentages decreased significantly during bathing and after bathing in comparison with those before bathing, but pulse rates and body temperatures increased significantly only during bathing. Subjective feelings containing cheerfulness, relaxation, and physical activity were measured using visual analog scale (VAS) and improvement of them was observed during and after bathing. These results indicate that radium hot spring bathing exerted beneficial effects in increase of flow-mediated dilation, decrease of blood pressure, and improvement of subjective feelings.},
 pages = {217--226},
 title = {ラジウム温泉浴が健常成人の血管内皮機能, 生理学的検査値および自覚的体感に及ぼす影響},
 volume = {126},
 year = {2012}
}