@article{oai:niigata-u.repo.nii.ac.jp:00009353, author = {五十嵐, 博中}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {Proton magnetic resonance spectroscopy (^1H-MRS) non-invasively provides in vivo biochemical infomlation of tissue metabolites.In acute stage of cerebral ischemia, N-acetyl aspartate (NAA), on of ^1H-MRS observable metabolite,declines gradually reflcted in energy impairment due to oxygen depletion. In our study, decline of NAA in the ischemic lesion linearly correlated with the time from the on set of ischemia. NAA can be utilized to time clock biomarker for the acute stage cerebral isehemia.}, pages = {177--183}, title = {プロトン磁気共鳴スペクトロスコピーから見た脳虚血病態}, volume = {127}, year = {2013} }