{"created":"2021-03-01T06:12:38.055694+00:00","id":8608,"links":{},"metadata":{"_buckets":{"deposit":"3f7d94fd-a0a3-4e7d-984d-5373cd3aaa2c"},"_deposit":{"id":"8608","owners":[],"pid":{"revision_id":0,"type":"depid","value":"8608"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00008608","sets":["453:456","471:537:538:907"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Generation and Analysis of Novel Dystonia Model Mice"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"497","bibliographicPageStart":"491","bibliographicVolumeNumber":"129","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"我々は, アクチン結合部位やチューブリン結合部位をもつ細胞骨格制御因子Dystonin (Dst)をコードする遺伝子を破壊したDst遺伝子トラップマウス(Dst^<GT>マウス)を作製し, ジストニア症状を示す遺伝性神経難病モデルマウスの確立に成功した. Dst^<Gt>ホモマウスは, 自然発生変異マウスのdystonia musculorumマウスと同様の運動障害と感覚神経の変性像を示した. 本マウスは, ジストニアなどの運動障害, 感覚性ニューロパチーの病態解析, および, 治療標的の同定に有用なモデルマウスであると考えられる.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"59939","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Takebayashi, Hirohide"}]},{"nameIdentifiers":[{"nameIdentifier":"59940","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Horie, Masao"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"竹林, 浩秀"}],"nameIdentifiers":[{"nameIdentifier":"59937","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"堀江, 正男"}],"nameIdentifiers":[{"nameIdentifier":"59938","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"129(9)_491-497.pdf","filesize":[{"value":"2.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"129(9)_491-497.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/8608/files/129(9)_491-497.pdf"},"version_id":"043f65d6-b6fb-47f3-9853-6b440e574ffc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ジストニア","subitem_subject_scheme":"Other"},{"subitem_subject":"dystonin","subitem_subject_scheme":"Other"},{"subitem_subject":"dystonia musculorumマウス","subitem_subject_scheme":"Other"},{"subitem_subject":"コンディショナル・ノックアウト実験","subitem_subject_scheme":"Other"},{"subitem_subject":"コンディショナル・レスキュー実験","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ジストニア症状を示す遺伝性神経難病モデルマウスの作製と解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ジストニア症状を示す遺伝性神経難病モデルマウスの作製と解析"},{"subitem_title":"ジストニア症状を示す遺伝性神経難病モデルマウスの作製と解析","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","907"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-12"},"publish_date":"2016-10-12","publish_status":"0","recid":"8608","relation_version_is_last":true,"title":["ジストニア症状を示す遺伝性神経難病モデルマウスの作製と解析"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:42:56.112004+00:00"}