@article{oai:niigata-u.repo.nii.ac.jp:00006689,
 author = {Uchiyama, Makoto and Otsuka, Takeshi and Sakai, Kaoru},
 issue = {2},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Sep},
 note = {In 39 children with orthostatic dysregulation (O. D.) and 28 control children aged 8 to 15 years, the relationship between plasma renin activity (PRA) after standing for 60 minutes and urinary sodium (Na) excretion was studied to elucidate the influence of Na balance on standing PRA in O. D.. Children with O. D. showed significant negative correlations between the standing PRA and 12-hour urinary Na/K ratio (P < 0.01), between the change in PRA on standing (standing PRA-supine PRA) and 12-hour urinary Na excretion (P < 0.001) and between the rate of increase in PRA on standing (standing PRA/supine PRA) and fractional excretion of filtered Na (FENa) (P < 0.0l). Control children, however, showed no significant correlations between them. Children with O. D. showed significant negative correlations between standing PRA and Na/creatinine ratio, Na/K ratio and FENa in urine collected during the 60-minute standing period (P < 0.05, P < 0.001, P <0.05, respectively). Control children, however, showed positive correlations between them. These findings suggest that the renin-angiotensin system may be activated to maintain circulatory homeostasis after prolonged standing according to the level of urinary Na excretion in O. D..},
 pages = {47--53},
 title = {Influence of urinary sodium excretion on plasma renin activity after prolonged standing in children with orthostatic dysregulation},
 volume = {34},
 year = {1986}
}