@article{oai:niigata-u.repo.nii.ac.jp:00006686, author = {Kuze, Shougo and Ito, Yusuke and Miyahara, Tatsuro}, issue = {3}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Dec}, note = {To clarify the oxidation of lactate and acetate contained in lactated and acetated Ringer's solutions, carbon dioxide productions from these compounds were investigated following a single intravenous injection of 1 mmol • kg^<-1> of [1-^<14>C] labelled DL-sodium lactate, L-sodium lactate or sodium acetate in unanesthetized rats. For DL-lactate, cumulative expired ^<14>CO_2 rates of total radioactivities of administered ^<14>C were, respectively, 16%, 37%, 63%, 70%, and 72%, at 15 minutes, 30 minutes, one hour, 2 hours and 6 hours following injection. These cumulative rates following DL-lactate administration were singnificantly lower for the first 40 minutes, compared with L-lactate and were only higher for the first 15 minutes, compared with acetate. These rates following DL-lactate administration were lower for doses of 1 mmol • kg^<-1> than for doses of 1μmol • kg^<-1> and also lower in fasting rats than in non-fasting animals. These phenomena were not observed for acetate.}, pages = {93--102}, title = {Expiration of radioactive carbon dioxide by rats after administration of isotopic lactate and acetate}, volume = {34}, year = {1986} }