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Ultrastructure of lipid droplets and nuclear inclusions in a pleomorphic liposarcoma
http://hdl.handle.net/10191/33572
http://hdl.handle.net/10191/33572aa804611-1342-492a-83f4-f9a9cbf71417
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-10-07 | |||||
タイトル | ||||||
タイトル | Ultrastructure of lipid droplets and nuclear inclusions in a pleomorphic liposarcoma | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Ultrastructure of lipid droplets and nuclear inclusions in a pleomorphic liposarcoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Suzuki, Toshimitsu
× Suzuki, Toshimitsu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We examined ultrastructures of a pleomorphic liposarcoma originating from the epicardium with special reference to lipid droplets and nuclear inclusions in the sarcoma cells. Consequently, four types of lipid droplets were discriminated in tumor cells. The most frequent type was mainly round lipid droplets with moderate electron density and diamaters of 0.7 to 2.4 μm. The second most frequent type was round or elliptical lipid droplets with a halo or a central shaggy core of moderate electron density. Their size measured about 1.0 μm in diameter. Droplets of the third type were irregular and highly osmiophilic and resembled lysosomes, though they lacked a limiting membrane. The size of these droplets ranged from 0.6 to 2.0 μm in the largest diameter. Droplets of the fourth type were mainly round. Each had a large central vacuole and the diameter was from 0.6 to 2.0 μm. The last two types were much less frequent than the former two. These findings might indicate deviated lipogenesis of the sarcoma cells, compared with lipogenesis in normal fat cells. Several types of nuclear inclusion bodies were found mainly in the mononuclear tumor cells. They were fundamentally round and multi-lamellar bodies, with diameters of about 400 to 800nm. In addition, some nuclear bodies contained small lipid droplets, an aggregate of microfilaments or a round dense central core, and they occasionaly showed vacuolation suggestive of their degeneration. Fusion of several kinds of the nuclear bodies was also found and resulted in an irregular large inclusion. The origin of the nuclear bodies is obscure but they seem to indicate high nuclear activities of the sarcoma cells. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 35, 号 1, p. 27-33, 発行日 1987-06 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |