{"created":"2021-03-01T06:10:35.448883+00:00","id":6672,"links":{},"metadata":{"_buckets":{"deposit":"3e588cbb-2143-4a30-87f1-d91bf3f8de9e"},"_deposit":{"id":"6672","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6672"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006672","sets":["453:456","471:537:568:655"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1987-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"61","bibliographicPageStart":"53","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We examined the reactivity of five murine monoclonal antibodies against myelin-associated glycoprotein (MAG) with the measles virus. One of the three antibodies recognizing the carbohydrate moiety of MAG and human mononuclear cells (MC-P2) could react with the measles ELISA antigen but another two reacting with peptide moiety could not. Eleven murine monoclonal antibodies against human lymphocytes including anti-Leu-7, and anti-MAG monoclonal IgM from a patient with demyelinating polyneuropathy could not react with the measles ELISA antigen. However, in an immunoblotting study, two bands, 56 kDa and 63 kDa, were stained by MC-P2, which differed from those -H(78 kDa), P(69 kDa) and NP(60 kDa) - stained by the serum of a patient with subacute sclerosing panencephalitis. It may be possible that the antigens reacting with MC-P2 are derived from Vero cells used in a culture of measles virus. Anti-MAG monoclonal murine antibody (MC-P2) could NOT react with measles virus proteins. Although previously we have found in studying by inhibition assay, that MC-P2 bind directly to or close to the Leu-7 epitope, a chemical feature of the antigen of MC-P2 and Leu-7 seems to be different.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tanaka, Masami"}],"nameIdentifiers":[{"nameIdentifier":"53891","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Keiko"}],"nameIdentifiers":[{"nameIdentifier":"53892","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishizawa, Masatoyo"}],"nameIdentifiers":[{"nameIdentifier":"53893","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inuzuka, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"53894","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Baba, Hiroko"}],"nameIdentifiers":[{"nameIdentifier":"53895","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sato, Shuzo"}],"nameIdentifiers":[{"nameIdentifier":"53896","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miyatake, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"53897","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"35(2)_53-61.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"35(2)_53-61.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6672/files/35(2)_53-61.pdf"},"version_id":"706056eb-76da-4f00-b039-1016cb621add"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"myelin-associated glycoprotein","subitem_subject_scheme":"Other"},{"subitem_subject":"measles virus","subitem_subject_scheme":"Other"},{"subitem_subject":"monoclonal antibody","subitem_subject_scheme":"Other"},{"subitem_subject":"glycoprotein","subitem_subject_scheme":"Other"},{"subitem_subject":"natural killer","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The characterization of murine monoclonal antibodies against myelin-associated glycoprotein (MAG) of the human brain : II The difference of the antigenic determinant between clone, MC-P2, reacting with human natural killer cells and Leu-7","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The characterization of murine monoclonal antibodies against myelin-associated glycoprotein (MAG) of the human brain : II The difference of the antigenic determinant between clone, MC-P2, reacting with human natural killer cells and Leu-7"},{"subitem_title":"The characterization of murine monoclonal antibodies against myelin-associated glycoprotein (MAG) of the human brain : II The difference of the antigenic determinant between clone, MC-P2, reacting with human natural killer cells and Leu-7","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","655"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-10-07"},"publish_date":"2015-10-07","publish_status":"0","recid":"6672","relation_version_is_last":true,"title":["The characterization of murine monoclonal antibodies against myelin-associated glycoprotein (MAG) of the human brain : II The difference of the antigenic determinant between clone, MC-P2, reacting with human natural killer cells and Leu-7"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:40:00.710632+00:00"}