@article{oai:niigata-u.repo.nii.ac.jp:00006662, author = {Sato, Yoshiaki and Hirohashi, Takeshi and Takeuchi, Shoshichi}, issue = {2}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Oct}, note = {The function of peptide hormone receptors on the trophoblastic cell membrane was analyzed, and the results obtained were as follows: 1) Receptors for hCG/LH, hPL/hGH, ACTH, insulin, and transferrin were recognized in trophoblastic cells. 2) Cyclic AMP levels in the tissue increased after administration of these hormones. 3) Binding capacity for these receptors was present in hydatidiform mole tissue, and its activity was stronger than that in normal placenta tissue. These findings strongly suggest that trophoblastic cells may have an autoregulatory mechanism through the membrane receptors, such as hCG/hLH and hPL/hGH, and this mechanism is working mainly through the cyclic AMP system.}, pages = {63--73}, title = {Hormone receptors in human placental cell membranes}, volume = {36}, year = {1988} }