@article{oai:niigata-u.repo.nii.ac.jp:00006656, author = {Ikarashi, Toshihiko and Sudo, Norihito and Kato, Masami and Hirasawa, Hirobumi and Ishii, Miwako and Kaneko, Hiroshi}, issue = {1}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Jun}, note = {This histopathological analysis was statistically performed between specimens of endometrial adenomatous hyperplasia (aH) regarded as a benign proliferative lesion and those of a well-differentiated type of endometrial adenocarcinoma (wC) with low-grade atypiam. Among the examined statistical indices of this histological atypism, the index of glandular area per unit area (IGA), the index of cellular area per unit area (lCA), and the index of gland-in-gland configuration per unit area (lGG) were statistically significant at 0.001, 0.001, and 0.02 levels (t-test), respectively. The multivariate statistical analysis with these reliable indices led the following quadratic discriminant functions: Q(x) = 0.01227x_1^2 - 0.07634x_2^2 - 0.45338x_3^2 -0.11596x_1x_2 +0.42307x_2x_3 +0.11860x_3x_1+2.08872x_1 +8.90431x_2 -16.82170x_3 -160.49600 (corrective discriminating rate of the aH and the wC : 0.857 and 1.000, respectively), Q'(x) = 0.03324x_1^2 -0.07129x_2^2 -0.02868x_4^2 -0.11888x_1x_2 +0.06813x_2x_4 +0.03027x_4x_1 -1.20861x_1 +6.62168x_2 - 0.98273x_4- 35.40290 (corrective discrimination of the aH and the wC: 1.000 and 1.000, respectively) (x_1 =IGA, x_2=ICA, x_3 =IGG, x_4=age). The multivariate statistical analysis of histopathology is valuable for the differentiation of the wC from the aH.}, pages = {51--54}, title = {Histopathological Differentiation of Endometrial Adenomatous Hyperplasia from a Well Differentiated Type of Endometrial Adenocarcinoma by Statistical Methods}, volume = {37}, year = {1989} }