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The Effects of Methylmercury on the Mitochondrial Energetics of Rat Skeletal Muscle : An in vivo ^<31>P-NMR Study
http://hdl.handle.net/10191/33536
http://hdl.handle.net/10191/335361005f1a7-918b-456b-9fee-ab77cdbb384f
名前 / ファイル | ライセンス | アクション |
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37(1)_45-50.pdf (778.2 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-10-06 | |||||
タイトル | ||||||
タイトル | The Effects of Methylmercury on the Mitochondrial Energetics of Rat Skeletal Muscle : An in vivo ^<31>P-NMR Study | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The Effects of Methylmercury on the Mitochondrial Energetics of Rat Skeletal Muscle : An in vivo ^<31>P-NMR Study | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Kuwabara, Takeo
× Kuwabara, Takeo× Yuasa, Tatsuhiko× Nagashima, Masaru× Igarashi, Hironaka× Yonemochi, Yousuke× Atsumi, Tetsushi× Miyatake, Tadashi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In this report it showed that methylmercury chrolide (MMC) affected the mitochondrial energetics of rat skeletal muscles in case of chronic intoxication. High energy phosphate compounds were measured by ^<31>P-NMR spectroscopy in the living rat hindleg skeletal muscle. Decreased value of phosphocreatine (PCr)/inorganic phosphate (Pi) ratio was observed in the resting muscle of the MMC intoxicated group, and suspend recovery of the ATP, PCr and intracellular pH after muscle contraction was found in the MMC intoxicated muscle. There was no difference in the ATP levels of the resting muscle between the control and MMC group. These results suggested that the synthesis of ATP was disturbed by the inhibition of mitochondrial respiration below TCA cycle. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 37, 号 1, p. 45-50, 発行日 1989-06 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |