@article{oai:niigata-u.repo.nii.ac.jp:00006628,
 author = {Tazawa, Toshio and Fujiwara, Hiroshi and Ito, Masaaki and Sato, Yoshio},
 issue = {2},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Jun},
 note = {Keratins expressed in carcinomas of the skin were immunohistochemically investigated using unfixed frozen specimens and several antikeratin monoclonal antibodies with different specificities. Only simple epithelial keratins were diffusely expressed in Merkel cell carcinomas, mammary and extramammary Peget's diseases, mucinous carcinomas of the skin, and cutaneous metastasis from gastric carcinomas, although the subtypes of simple epithelial keratins were somewhat different among these carcinomas. On the other hand, both simple and stratified epithelial keratins were variously expressed in squamous cell carcinomas, Bowen's disease, basal cell epithelioma and eccrine adenocarcinomas, although considerable differences in the staining patterns were observed in these carcinomas. It is suggested that the keratin expressions in carcinomas of the skin may imitate those in the corresponding epithelia of normal skin, although the contents of the keratins of the carcinomas are not always the same as those in the normal epithelia. Immunohistochemical examination seems to be of great value for the differential diagnosis of carcinomas of the skin.},
 pages = {75--84},
 title = {Immunohistochemical Study on Differentiations of Carcinomas of the Skin Using Antikeratin Monoclonal Antibodies},
 volume = {38},
 year = {1990}
}