@article{oai:niigata-u.repo.nii.ac.jp:00006620,
 author = {Yoshikawa, Keiji and Mishina, Takeshi and Matsubara, Youichi and Muto, Terukazu},
 issue = {4},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Dec},
 note = {The rate of the hepatic glucose production was isotopically determined in combination with the measurement of plasma amino acid concentrations in completely pancreatectomized dogs. Marked hyperaminoacidemia mainly consisting of elevated glucogenic amino acids was observed regardless of the postoperative insulin replacement. Reduction of the elevated amino acids (except for the branched chain amino acids) by the exogenous glucagon was also observed. Particularly in cases where the plasma glucose level had been maintained at normal levels by the insulin, the decreasing of the plasma amino acid concentrations was associated with enhanced hepatic glucose production, indicating that the cause of hyperaminoacidemia in totally pancreatectomized dogs is inhibited gluconeogenesis from amino acids due to glucagon deficiency.},
 pages = {175--185},
 title = {The Cause of Hyperaminoacidemia in Completely Pancreatectomized Dogs},
 volume = {38},
 year = {1990}
}