@article{oai:niigata-u.repo.nii.ac.jp:00006614, author = {Kihara, Itaru and Yaoita, Eishin and Yamamoto, Tadashi}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {The process of glomerular adhesion to Bowman's capsule was morphologically investigated in aging rats. The results showed that segmentally hyperplastic parietal epithelial cells of the Bowman's capsule extended their cytoplasms to the segments of the glomerular capillary and covered the areas of the denuded part of the glomerular basement membrane from which the glomerular epithelial cells had been detached. The separation of the glomerular epithelial cells from the underlying glomerular basement membrane allowed local passage of macromolecular substances across the capillary wall. In conclusion, datachment and eventual cell death of the glomerular epithelial cells, together with various factors in exuded macromolecular substances relate directly to the subsequent proliferation of parietal epithelial cells. Thus, glomerular adhesion should be considerd as a multistep process.}, pages = {69--80}, title = {Cellular Processes of Glomerular Adhesion in Aged Rats}, volume = {38(Supplement)}, year = {1990} }