@article{oai:niigata-u.repo.nii.ac.jp:00006605, author = {Sakai, Masaharu and Fuwano, Seiichi and Karakida, Takeo and Yamada, Yukio and Homma, Shinji}, issue = {1}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {Thyrotropin-releasing hormone (TRH) was measured in the pancreas, gastrointestinal tract and hypothalamus of streptozotocin diabetic rats. While glucagon concentrations in the pancreas were similar between normal and diabetic rats, TRH and insulin were remarkably reduced in the diabetic pancreas, suggesting TRH presence in B-cells of the pancreatic islets. In diabetic rats, plasma T_3 and T_4 levels were remarkably reduced. However, TRH concentrations in the gastrointestinal tract, hypothalamus and plasma were similar for diabetic and normal animals.}, pages = {21--27}, title = {Thyrotropin-Releasing Hormone (TRH) Changes in the Pancreas, Gastrointestinal Tract, Hypothalamus and Plasma of Streptozotocin Diabetic Rats}, volume = {39}, year = {1991} }