@article{oai:niigata-u.repo.nii.ac.jp:00006586, author = {Yamaguchi, Hisomu}, issue = {4}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Dec}, note = {A four item screening system was established to detect monoclonal serum proteins: that is, a marked increase in serum total protein over 10 g/100ml, abnormally low values of TTT and ZTT or their marked dissociation, and dissociation of the results of urinary albustix and sulfosalicylic acid tests. A high rate of association of myeloma with other malignant tumors was noted in our series. Twelve malignancies in 11 patients were confirmed in 43 cases with multiple myeloma in 1980. Recently succesive resections of the carcinomas of the sigmoid colon, ascending colon and stomach (double cancers of the stomach) were performed on an 84-year-old male, who is still alive. Treatment of multiple myeloma should not be too aggressive. Maintenance therapy with low dose anticancer drugs was necessary in most of the cases.}, pages = {147--152}, title = {Immunoglobulinopathy : Its Diagnosis and Development}, volume = {39}, year = {1991} }