{"created":"2021-03-01T06:10:28.595687+00:00","id":6564,"links":{},"metadata":{"_buckets":{"deposit":"f3e51e94-d55d-4449-88f5-c43243e83f3d"},"_deposit":{"id":"6564","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6564"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006564","sets":["453:456","471:537:568:636"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"83","bibliographicPageStart":"79","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Serum biliary ALP isoenzyme (ALP_1) was detected in 29.7% of rheumatoid arthritis (RA) patients studied, whereas it was undetectable in osteo-arthrosis patients. The positive activity of ALP_1 in the serum was accompanied by significant but mild increases in γ-GTP and LAP. These findings suggest that RA has an influence on the biliary tract. Furthermore, elevations of ALP_2 , ALP_3 , RAHA, CRP, ESR and IgA as well as a lowering of grip strength, stage and class in the ALP_1-positive RA patients were more marked than in the ALP_1-negative RA patients. These data suggest that the disease activity of RA is higher, and the bone resorption mechanism more enhanced in ALP_1-positive than in ALP_1-negative RA patients. There was no significant relationship between ALP_1 and AMA or ANA. This suggests that the possible overlapping of RA and PBC or SLE could be excluded from the reasons of the detection of ALP_1 activity.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Aida, Sumihisa"}],"nameIdentifiers":[{"nameIdentifier":"53506","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"40(2)_79-83.pdf","filesize":[{"value":"667.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"40(2)_79-83.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6564/files/40(2)_79-83.pdf"},"version_id":"7f322fb1-b78c-4cd1-9cb6-c86d0758bcb4"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relation between Rheumatoid Arthritis and Alkaline Phosphatase Isoenzymes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relation between Rheumatoid Arthritis and Alkaline Phosphatase Isoenzymes"},{"subitem_title":"Relation between Rheumatoid Arthritis and Alkaline Phosphatase Isoenzymes","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","636"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-09-18"},"publish_date":"2015-09-18","publish_status":"0","recid":"6564","relation_version_is_last":true,"title":["Relation between Rheumatoid Arthritis and Alkaline Phosphatase Isoenzymes"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:39:52.150716+00:00"}