ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "adbfda0c-15a5-4f96-a924-9a5bdbe76a65"}, "_deposit": {"id": "6549", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6549"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006549", "sets": ["456", "634"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "164", "bibliographicPageStart": "157", "bibliographicVolumeNumber": "40", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "After transferring spleen cells from C57BL/6 (B6) mice into C57BL/10Cr (B10Cr) mice, secondary responses to trinitrophenylated lipopolysaccharide in the recipient B10Cr mice were investigated. Though we observed a primary response to TNP-LPS in the recipient B10Cr mice to which spleen cells of B6 mice were transferred, cells primed with TNP-LPS caused stronger IgG responses than virgin cells. The production and maintenance of memory B cells were hardly affected in glioma bearing mice. However, the isotype-switch of IgM to IgG on a secondary response appeared weaker in\\nmemory B cells from mice bearing brain tumors than in those from normal B6 mice. In spite of the memory-cell transfer of B6 mice, glioma-bearing B10Cr mice could not maintain the immunological memory. The isotype-switch was also incomplete in these mice. The antigen-presenting ability of peritoneal exudate cells from glioma-bearing B6 mice was also weaker than that of normal B6 mice. Thus, we observed a disturbance of antibody responses to the thymus-independent antigens in glioma-bearing mice, which is attributed to the impaired antigen presenting ability of the macrophages.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yoshida, Seiichi"}], "nameIdentifiers": [{"nameIdentifier": "53441", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Ryuichi"}], "nameIdentifiers": [{"nameIdentifier": "53442", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "40(4)_157-164.pdf", "filesize": [{"value": "1.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1200000.0, "url": {"label": "40(4)_157-164.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6549/files/40(4)_157-164.pdf"}, "version_id": "cd1be795-83aa-4501-ae0b-d70e438732a8"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors"}, {"subitem_title": "Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "634"], "permalink_uri": "http://hdl.handle.net/10191/33393", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-09-18"}, "publish_date": "2015-09-18", "publish_status": "0", "recid": "6549", "relation": {}, "relation_version_is_last": true, "title": ["Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors"], "weko_shared_id": null}
  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.40 No.4

Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors

http://hdl.handle.net/10191/33393
http://hdl.handle.net/10191/33393
16050e2a-88c5-4cfe-ba41-fe32086ad12c
名前 / ファイル ライセンス アクション
40(4)_157-164.pdf 40(4)_157-164.pdf (1.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-09-18
タイトル
タイトル Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors
タイトル
言語 en
タイトル Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Yoshida, Seiichi

× Yoshida, Seiichi

WEKO 53441

Yoshida, Seiichi

Search repository
Tanaka, Ryuichi

× Tanaka, Ryuichi

WEKO 53442

Tanaka, Ryuichi

Search repository
抄録
内容記述タイプ Abstract
内容記述 After transferring spleen cells from C57BL/6 (B6) mice into C57BL/10Cr (B10Cr) mice, secondary responses to trinitrophenylated lipopolysaccharide in the recipient B10Cr mice were investigated. Though we observed a primary response to TNP-LPS in the recipient B10Cr mice to which spleen cells of B6 mice were transferred, cells primed with TNP-LPS caused stronger IgG responses than virgin cells. The production and maintenance of memory B cells were hardly affected in glioma bearing mice. However, the isotype-switch of IgM to IgG on a secondary response appeared weaker in\nmemory B cells from mice bearing brain tumors than in those from normal B6 mice. In spite of the memory-cell transfer of B6 mice, glioma-bearing B10Cr mice could not maintain the immunological memory. The isotype-switch was also incomplete in these mice. The antigen-presenting ability of peritoneal exudate cells from glioma-bearing B6 mice was also weaker than that of normal B6 mice. Thus, we observed a disturbance of antibody responses to the thymus-independent antigens in glioma-bearing mice, which is attributed to the impaired antigen presenting ability of the macrophages.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 40, 号 4, p. 157-164, 発行日 1992-12
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 19:35:47.775587
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3