{"_buckets": {"deposit": "adbfda0c-15a5-4f96-a924-9a5bdbe76a65"}, "_deposit": {"id": "6549", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6549"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006549"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "164", "bibliographicPageStart": "157", "bibliographicVolumeNumber": "40", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "After transferring spleen cells from C57BL/6 (B6) mice into C57BL/10Cr (B10Cr) mice, secondary responses to trinitrophenylated lipopolysaccharide in the recipient B10Cr mice were investigated. Though we observed a primary response to TNP-LPS in the recipient B10Cr mice to which spleen cells of B6 mice were transferred, cells primed with TNP-LPS caused stronger IgG responses than virgin cells. The production and maintenance of memory B cells were hardly affected in glioma bearing mice. However, the isotype-switch of IgM to IgG on a secondary response appeared weaker in\\nmemory B cells from mice bearing brain tumors than in those from normal B6 mice. In spite of the memory-cell transfer of B6 mice, glioma-bearing B10Cr mice could not maintain the immunological memory. The isotype-switch was also incomplete in these mice. The antigen-presenting ability of peritoneal exudate cells from glioma-bearing B6 mice was also weaker than that of normal B6 mice. Thus, we observed a disturbance of antibody responses to the thymus-independent antigens in glioma-bearing mice, which is attributed to the impaired antigen presenting ability of the macrophages.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yoshida, Seiichi"}], "nameIdentifiers": [{"nameIdentifier": "53441", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Ryuichi"}], "nameIdentifiers": [{"nameIdentifier": "53442", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "filename": "40(4)_157-164.pdf", "filesize": [{"value": "1.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 12000000, "url": {"label": "40(4)_157-164.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6549/files/40(4)_157-164.pdf"}, "version_id": "cd1be795-83aa-4501-ae0b-d70e438732a8"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors"}, {"subitem_title": "Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/634"], "permalink_uri": "http://hdl.handle.net/10191/33393", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2015-09-18"}, "publish_date": "2015-09-18", "publish_status": "0", "recid": "6549", "relation": {}, "relation_version_is_last": true, "title": ["Secondary Antibody Responses to Thymus-independent Antigens in Mice with Brain Tumors"], "weko_shared_id": null}