@article{oai:niigata-u.repo.nii.ac.jp:00006541, author = {Gotoh, Toshiaki}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {1. The embryogenesis and anatomy of the vesicoureteric junction (VUJ) were reviewed and the role of the periureteric sheath was emphasized. 2. An unstable bladder was found to be associated with half of the cases of "primary" reflux. It was suggested that an unstable bladder somehow influences the integrity of the VUJ to cause reflux and/or its aggravation in the presence of an immature VUJ. When reflux is associated with an unstable bladder, its spontaneous cure is highy likely even if the reflux is severe. Conversely, unstable bladder is associated with a high risk of the failure or development of complications of antireflux surgery. 3. Our experience in 23 patients with the detection of occult reflux by bethanechol-aided VCU was presented. This appears to be a sensitive method for detecting occult reflux, as emphasized by our recent ureteroneocystostomy results in which postoperative contralateral reflux was hardly seen after unilateral surgery. 4. In contrast, the sensitivity of RI-VCU for detecting occult reflux seems to be low in both control and bethanechol-aided studies.}, pages = {17--22}, title = {Role of the Vesicoureteric Junction and Unstable Bladder in Vesicoureteric Reflux : Value of Bethanechol Chloride-aided Voiding Cystourethrography in Detecting Occult Reflux}, volume = {40(Supplement)}, year = {1992} }