@article{oai:niigata-u.repo.nii.ac.jp:00006534, author = {Takagi, Akio and Ito, Kazuhiko and Suzuki, Eiichi and Arakawa, Masaaki and Emura, Iwao}, issue = {1}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {Flow cytometric nuclear DNA content (DNA ploidy) was measured in paraffin-embedded surgical specimens of 87 patients with primary lung cancer. Of the 87 tumor tissues, 17 (19.5%) showed a normal DNA stemline (DNA diploidy), and 70 (80.5%) an abnormal DNA stemline (DNA aneuploidy). Patients with DNA aneuploid tumors had significantly shorter survival times than those with DNA diploid tumors (p <0.001). This study confirmed the high incidence of DNA aneuploidy as well as its prognostic implication in primary lung cancer patients. DNA aneuploidy seems to be a useful parameter for evaluating the degree of lung cancer malignancy.}, pages = {11--16}, title = {A Study of Flow Cytometric Nuclear DNA Content in Lung Cancer : The Incidence of DNA Aneuploidy and Its Prognostic Implications}, volume = {41}, year = {1993} }