@article{oai:niigata-u.repo.nii.ac.jp:00006528, author = {Hayashi, Jun-ichi and Oguma, Fumiaki and Tsuchida, Sho-ichi and Fujita, Yasuo and Nakazawa, Satoshi and Miyamura, Haruo and Eguchi, Shoji}, issue = {2}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Jun}, note = {A ten-year period of using St. Jude Medical (SJM) prosthetic heart valves at Niigata University Hospital was reviewed. Between December 1979 and August 1990, 261 patients, 118 males and 143 females, ages ranging 6-75 years, underwent SJM prosthetic valve replacement. Aortic valve replacement was performed in 72 patients, mitral valve replacement in 140 patients, combined aortic and mitral valve replacement in 37 patients, and miscellaneous valve replacement in 12 patients. The actuarial survival rates at 10 years including hospital deaths were: AVR; 86.1±4.4%, MVR; 92.0±2.5%, and AVR+MVR; 78.4±6.1%. The causes of death were cardiac failure in 11 patients, sudden death in 2 patients, infection in 4 patients, carcinoma in 3 patients, and miscellaneous in 6 patients. Eleven patients suffered from thromboembolic episodes 3 months to 8 years after surgery. The actuarial thromboembolism- free rates at 10 years were: AVR; 96.2± 2.6%, MVR; 91.6±3.0% and AVR+MVR; 95.5±4.4%. Four patients suffered from acute intravascular hemolysis and underwent a second replacement. Three of the 4 patients who showed chronic hemolysis were able to avoid reoperation due to successful drug therapy and limited daily activity. Of the 5 patients who developed prosthetic valve endocarditis, 3 patients survived without reoperation. Late postoperative cardiac catheterization revealed the excellent performance of prosthetic heart valves, and adequate left ventricular performance in all but 8 patients. Six patients developed malignant diseases, and 3 patients endured radical resection. In conclusion, excellent performance and high-quality survival rates were attainable with SJM prostheses, due to their flow characteristics, and to the improved postoperative management.}, pages = {81--89}, title = {Review of Ten Years' Use of St. Jude Medical Prosthetic Valve Replacement and Postoperative Management at Niigata University Hospital}, volume = {41}, year = {1993} }