@article{oai:niigata-u.repo.nii.ac.jp:00006516, author = {Canine, Santos Marcia and Mendes, Boasquevisque Edson and Bernardo-Filho, Mario}, issue = {4}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Dec}, note = {This study investigated whether the binding sites of ^<51>Chromium (^<51>Cr) and ^<99m>Technetium (^<99m>Tc) to the beta chain on the hemoglobin were the same. Previous treatment of red blood cells (RBC) with ^<51>Cr did not interfere with the percentage of ^<99m>Tc-labeled RBC. When the previous treatment of RBC with ^<99m>Tc was carried out, the percentage of ^<51>Cr-labeled RBC was not altered. Previous treatment with large amounts of non-radioactive chromium (^<50>Cr) did not seem to alter the percentage of the ^<99m>Tc-labeled RBC, except for the highest concentration of ^<50>Cr. In this case RBC showed great morphological changes in optical microscopy. Our results show that, although ^<51>Cr and ^<99m>Tc bind to the beta chain of the hemoglobin, they probably bind at different target sites.}, pages = {189--192}, title = {Binding Sites of ^<51>Chromium and ^<99m>Technetium to Red Blood Cells : A Comparative Study}, volume = {41}, year = {1993} }