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Passive Immune Transfer of Murine Tumor-dormant Disposition
http://hdl.handle.net/10191/33232
http://hdl.handle.net/10191/33232e18d725c-9f5d-4e35-8519-b92964648de0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
42(1)_7-12.pdf (592.0 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-09-04 | |||||
| タイトル | ||||||
| タイトル | Passive Immune Transfer of Murine Tumor-dormant Disposition | |||||
| タイトル | ||||||
| タイトル | Passive Immune Transfer of Murine Tumor-dormant Disposition | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Sato, Norimitsu L.
× Sato, Norimitsu L.× Kato, Akiko |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | 1) subcutaneously inoculated Ehrlich Ascites Tumor (EAT) remained dormant in a ddY-drm mouse, while it grew and formed a solid tumor in a ddY-prg mouse. H-2 haplotype of ddY-drm was s and that of ddY-prg was q, which separated by two-way (EAT-dormant or EAT-progressive) selection over F+16 of a closed colony stock of ddY mice. Ly-1 and Ly-2 haplotypes, however, were not clearly distinct, showing a reduced expression of Ly-1.1 (11.0%), -1.2 (48.0%), Ly2.1 (32.0%) and -2.2 (32.0%) in the ddY-drm mouse while revealing a multi-expression of Ly-1.1 (70.4%), -1.2 (75.8%), Ly-2.1 (65.5%) and -2.2 (67.7%) in the ddY-prg mouse. 2) Adoptive immunotherapy against subcutaneous EAT outgrowth in the ddY-prg mouse was successfully undertaken beyond the difference of H-2 haplotype by transfer of ddY-drm spleen cells. Spleen cells from EAT-immunized ddY-drm mice were strongly effective. By combination with another mouse strain, such adoptive immunotherapy was unsuccessful except in a case of combination such as C57BL/6 (EAT-regressive) and C57BL/6-nu/nu (EAT-progressive). Some genetic background data were suggested for the success of the passive immune transfer of the murine tumor-dormant disposition. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 42, 号 1, p. 7-12, 発行日 1994-03 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
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| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
