@article{oai:niigata-u.repo.nii.ac.jp:00006495, author = {Yamagiwa, Iwao and Iwafuchi, Makoto and Washio, Masahiko}, issue = {3}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Sep}, note = {Results of routine liver function tests performed prior to Kasai's operation within 12 weeks after birth in 50 patients with extrahepatic biliary atresia during 1981 to 1992 were retrospectively analyzed. Thirty neonatal patients without cholestatic disease served as the control group. Total bilirubin, direct bilirubin and gamma-glutamyl transpeptidase levels were significantly different between the extrahepatic biliary atresia and control groups within I week after birth (16.1±3.2 mg/dl vs. 11.6±4.7 mg/dl, 4.6±2.6 mg/dl vs. 0.6±0.2 mg/dl, 701±228 IU/1 vs. 56±21IU/1 respectively). Conversely, no differences were observed between them in the levels of aminotransferases within 2 weeks after birth. These data suggest that no hepatocellular damage occurs at least 2 weeks after birth in extrahepatic biliary atresia, and that the determination of bilirubin and gamma-glutamyl transpeptidase levels within 1 week after birth enable us to distinguish patients with extrahepatic biliary atresia from physiologic jaundice during this period.}, pages = {109--113}, title = {The Usefulness of Routine Liver Function Tests in the Discrimination of Extrahepatic Biliary Atresia from Physiologic Jaundice in the Early Neonatal Period}, volume = {42}, year = {1994} }