@article{oai:niigata-u.repo.nii.ac.jp:00006489, author = {Aono, Takashi and Tsukada, Kazuhiro and Sakaguchi, Takeo and Ishiduka, Dai and Suzuki, Tsutomu and Hatakeyama, Katsuyoshi}, issue = {4}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Dec}, note = {Liver function was examined in 60 patients with a 0.1 and 0.5 mg/kg intravenous bolus of indocyanine green (ICG). When plasma ICG concentrations were measured 3, 5, 7, 10 and 15 min after time zero, the removal slope for ICG was consistently exponential for the 15-min observation period. The slope was similar between the two ICG administrations in log scale. When disappearance rates of ICG 10 min after time zero between the 0.1 and 0.5 mg/kg tests were compared, a significant correlation (p<0.01) was obtained. Serum bilirubin fluctuation ranging from 0.4 to 3.7 mg/dl had no meaningful effect on the efficacy of the 0.1 mg/kg ICG test. These results suggest that an ICG 0.1mg/kg test is accurate enough to estimate the liver function, and has potential value for clinical application.}, pages = {165--169}, title = {Utilization of Low Dose Indocyanine Green Test for Evaluating Liver Function}, volume = {42}, year = {1994} }