@article{oai:niigata-u.repo.nii.ac.jp:00006469, author = {Ajioka, Yoichi and Watanabe, Hidenobu and Kobayashi, Masaaki and Yoshida, Mituhiro and Genta, Robert M.}, issue = {2}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Jun}, note = {8624 tubular adenomas from 9 patients with familial adenomatosis coli were investigated to elucidate the mode of their macroscopic development. Our data indicate that most tubular adenomas remain smaller than 5 mm, suggesting that those larger than 5 mm detected clinically may already have deviated from the expected natural history of benign adenomas. Their initial macroscopic configuration appears to be the flat or sessile type, and they seem to change their macroscopic configurations to subpedunculated as they attain a size between 5 and 7 mm. Adenomas larger than 8 mm appear to take a pedunculated shape. This mode of macroscopic development may be affected by the location of adenomas, and tends to occur in adenomas of a smaller size in the rectum, sigmoid and ascending colon than in the rest of the organ.}, pages = {63--68}, title = {Macroscopic Characteristics of Tubular Adenomas in Familial Adenomatosis Coli : The Relationship between Size, Gross Configuration and Location}, volume = {43}, year = {1995} }