@article{oai:niigata-u.repo.nii.ac.jp:00006451, author = {Nishimaki, Tadashi and Tanaka, Otsuo and Suzuki, Tsutomu and Aizawa, Kikuo and Watanabe, Kazuo and Nakagawa, Satoru and Hatakeyama, Katsuyoshi and Watanabe, Hidenobu}, issue = {1}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {A 56-year-old male patient underwent neoadjuvant chemotherapy with cisplatin, 5-fluorouracil, and leucovorin for a constricting esophageal carcinoma with extensive lymph node metastases. A Columnar lower esophageal epithelium measuring 3.3 cm in length was observed to be distinct from the esophageal tumor at endoscopy on the 29th day following the initiation of chemotherapy. The patient underwent palliative esophagectomy following three cycles of neoadjuvant chemotherapy. The resected specimen revealed a concomitant mucoepidermoid carcinoma of the esophagus and Barrett's esophagus (BE) characterized by columnar epithelium with intestinal metaplasia. The clinicopathologic details of this rare association of Barrett's metaplasia with esophageal mucoepidermoid carcinoma are presented, the possible genesis of Barrett's esophagus in relation to the development of mucoepidermoid carcinoma is discussed, and the literature is reviewed.}, pages = {51--57}, title = {Barrett's Esophagus Associated with Mucoepidermoid Carcinoma Arising in the Esophageal Squamous Epithelium}, volume = {44}, year = {1996} }