ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "89fde38a-7911-4e8a-971b-035a5d3e35b7"}, "_deposit": {"id": "6448", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6448"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006448", "sets": ["456", "620"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1996-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "42", "bibliographicPageStart": "37", "bibliographicVolumeNumber": "44", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Arsenical keratosis (AK) is a common early sign of chronic arsenicism. The association between arsenicism and Bowen\u0027s disease is well documented, but a definitive understanding of the relation between AK and Bowen\u0027s disease remains elusive. In this study, eight cases of AK were examined immunohistologically with antibodies for cytokeratins, epidermal growth factor receptor, erbB2 protein, c-myc protein, and ki-67. An in situ hybridization study for c-myc, v-erb-B, and erbB2 mRNA was also performed. Bowen\u0027s disease (16 cases) and normal skin (3 cases) of arsenic ingesters, and Bowen\u0027s disease (15 cases) and seborrheic keratosis (15 cases) without arsenic exposure served as controls. AK revealed a similar reaction to Bowen\u0027s disease, with characteristic positive cells for ki-67 antigen and c-myc mRNA in the suprabasal layers. These findings demonstrate a close relationship between AK and Bowen\u0027s disease.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Fujiwara, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "52974", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tazawa, Toshio"}], "nameIdentifiers": [{"nameIdentifier": "52975", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Ayako"}], "nameIdentifiers": [{"nameIdentifier": "52976", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Masaaki"}], "nameIdentifiers": [{"nameIdentifier": "52977", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "44(1)_37-42.pdf", "filesize": [{"value": "1.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1900000.0, "url": {"label": "44(1)_37-42.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6448/files/44(1)_37-42.pdf"}, "version_id": "5aa46b1e-2dde-49b8-ae0f-a0a9b0eb3fdf"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "arsenic", "subitem_subject_scheme": "Other"}, {"subitem_subject": "arsenical keratosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Bowen\u0027s disease", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis"}, {"subitem_title": "An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "620"], "permalink_uri": "http://hdl.handle.net/10191/33156", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-08-27"}, "publish_date": "2015-08-27", "publish_status": "0", "recid": "6448", "relation": {}, "relation_version_is_last": true, "title": ["An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis"], "weko_shared_id": null}
  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.44 No.1

An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis

http://hdl.handle.net/10191/33156
http://hdl.handle.net/10191/33156
4f9777a2-6001-453a-a2c2-24b2ae7a683d
名前 / ファイル ライセンス アクション
44(1)_37-42.pdf 44(1)_37-42.pdf (1.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-08-27
タイトル
タイトル An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis
タイトル
言語 en
タイトル An Immunohistological and in Situ Hybridization Study of Arsenical Keratosis
言語
言語 eng
キーワード
主題Scheme Other
主題 arsenic
キーワード
主題Scheme Other
主題 arsenical keratosis
キーワード
主題Scheme Other
主題 Bowen's disease
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Fujiwara, Hiroshi

× Fujiwara, Hiroshi

WEKO 52974

Fujiwara, Hiroshi

Search repository
Tazawa, Toshio

× Tazawa, Toshio

WEKO 52975

Tazawa, Toshio

Search repository
Yamamoto, Ayako

× Yamamoto, Ayako

WEKO 52976

Yamamoto, Ayako

Search repository
Ito, Masaaki

× Ito, Masaaki

WEKO 52977

Ito, Masaaki

Search repository
抄録
内容記述タイプ Abstract
内容記述 Arsenical keratosis (AK) is a common early sign of chronic arsenicism. The association between arsenicism and Bowen's disease is well documented, but a definitive understanding of the relation between AK and Bowen's disease remains elusive. In this study, eight cases of AK were examined immunohistologically with antibodies for cytokeratins, epidermal growth factor receptor, erbB2 protein, c-myc protein, and ki-67. An in situ hybridization study for c-myc, v-erb-B, and erbB2 mRNA was also performed. Bowen's disease (16 cases) and normal skin (3 cases) of arsenic ingesters, and Bowen's disease (15 cases) and seborrheic keratosis (15 cases) without arsenic exposure served as controls. AK revealed a similar reaction to Bowen's disease, with characteristic positive cells for ki-67 antigen and c-myc mRNA in the suprabasal layers. These findings demonstrate a close relationship between AK and Bowen's disease.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 44, 号 1, p. 37-42, 発行日 1996-03
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 19:38:26.810670
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3