@article{oai:niigata-u.repo.nii.ac.jp:00006447, author = {Kodama, Shoji and Kase, Hiroaki and Tanaka, Kenichi}, issue = {1}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {Diagnostic conization is performed especially in the case of endocervical lesions with early cervical neoplasia because it is diffiucult to biopsy endocervical canal lesions in such cases. We analyzed the indications and usefulness of diagnostic conization by comparing its results with those of preoperative cytology and histology. The subjects consisted of 69 patients who underwent diagnostic conization at our hospital between January 1, 1988 and August 31, 1995. Preoperative histology by biopsy showed under diagnosis in 34 (49.3%), and over diagnosis in 16 (23.2%) compared with the diagnosis by conization, respectively. When the cytology indicated mild or moderate dysplasia and biopsy indicated moderate dysplasia or a less advanced lesion, no diagnostic conization was required because the final diagnosis bore out the earlier indications. When the cytology indicated carcinoma in situ (CIS) or invasive cancer, diagnostic conization was required because CIS or microinvasive cancer was ultimately diagnosed even if the biopsy showed no neplastic change. When the cytology indicated severe dysplasia to invasive carcinoma, 18.2% of the patients diagnosed as moderate dysplasia or a less advanced lesion by conization did not undergo hysterectomy. This study showed indication for diagnostic conization and the usefulness of conization for the reservation of the uterus.}, pages = {31--36}, title = {The Indication and Evaluation of Diagnostic Conization of the Uterine Cervical Neoplasia}, volume = {44}, year = {1996} }