@article{oai:niigata-u.repo.nii.ac.jp:00006427,
 author = {Higuchi, Shoichi and Fujita, Shozo and Sueyama, Hiroo and Ohkubo, Masaki and Sakai, Kunio},
 issue = {3},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Sep},
 note = {The effects of radiation in combination with either 5-fluorouracil (5-FU), cisplatin (CDDP), or both on FM3A cell survival were evaluated in vitro. Cell survival following treatment with the drugs and/or radiation was determined by colony formation assays. Prolonged exposure of 5-FU as well as CDDP was very effective in killing cells. The combination of radiation with 24-hour continuous exposure of the drugs resulted in radiosensitization, while 1-hour pulse exposure of CDDP combined with radiation did not enhance cell killing, indicating that radiosensitization by CDDP may require a longer duration of drug exposure following irradiation. In addition, concurrent continuous exposure of 5-FU and CDDP in combination with radiation resulted in a greater radiosensitizing effect.},
 pages = {141--145},
 title = {Radiosensitization of FM3A Cells by 5-Fluorouracil Plus Cisplatin},
 volume = {44},
 year = {1996}
}