@article{oai:niigata-u.repo.nii.ac.jp:00006420,
 author = {Chinushi, Masaomi and Aizawa, Yoshifusa and Abe, Akira and Shiba, Masami and Washizuka, Takashi and Tamura, Makoto and Igarashi, Yutaka and Kusano, Yoriko and Niwano, Shinichi and Shibata, Akira and Watanabe, Hiroshi and Eguchi, Shoji},
 issue = {4},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Dec},
 note = {Implantable cardioverter-defibrillators (ICD) were implanted in 11 patients with drug refractory ventricular tachyarrhythmias. Both ventricular fibrillation (VF) and sustained ventricular tachycardia (VT) were documented in 4 of the 11 patients, and VF or VT was observed in the other 4 and 3 patients, respectively. The mean left ventricular ejection fraction of the 11 patients was 40±22%; underlying heart diseases were observed in 9 patients, old myocardial infarction in 4 patients, and dilated cardiomyopathy in 5 patients. Transvenous ICD was implanted in 10 patients (91%), but because of a high defibrillation threshold, two epicardial patch electrodes were necessary in the remaining one patient. During the operative procedure, no complications were observed except for an episode of vasospastic angina in one patient with normal coronary arteries. In 3 patients with severe left ventricular dysfunction, VT with clinical QRS morphology was frequently observed within a few days after surgery, and additional antiarrhythmic drug therapy and changes in the detection mode of VF were required. Subclavian crash syndrome was noticed 26 months after ICD implantation in one patient. During the follow-up periods of 6 to 54 months (the mean being 28.7 ± 20.6 months), VT and/or VF recurred in 6 of the 11 patients, and these tachycardias were terminated by appropriate ICD treatment. One patient died due to refractory heart failure 7 months after ICD implantation. Transvenous implantation was easier and judged to be the first choice procedure for ICD implantation. ICD is a feasible therapy for drug refractory ventricular tachyarrhythmias, but special management is required to control VT/VF by antiarrhythmic drug or to detect complications.},
 pages = {199--207},
 title = {Initial Experiences of Implantable Cardioverter-Defibrillator Treatment in Patients with Ventricular Tachyarrhythmias},
 volume = {44},
 year = {1996}
}