@article{oai:niigata-u.repo.nii.ac.jp:00006412, author = {Saitoh, Atsushi and Aoyagi, Yutaka and Mori, Shigeki and Suda, Takeshi and Suzuki, Yasufumi and Sekine, Chuichi and Asakura, Hitoshi}, issue = {1}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Mar}, note = {Twelve samples of α_1-anlitrypsin (AAT) were purified from six patients with hepatocellular carcinoma, one with pancreatic cancer and five healthy individuals, and subjected to the measurement of the fucosylated sugar chain. We compared different results from crossed immunoaffinoelectrophoresis (CIAE) with Lens culinaris agglutinin (LCA) and by the carbohydrate analysis of high-performance liquid chromatography (HPLC) with the pylidylaminated (PA・) oligosaccharides obtained from each AAT. A significantly good correlation was obtained between the percentage of PA-fucosylated biantennary sugar chains in whole PA-oligosaccharides of each AAT sample by HPLC analysis and the percentage of LCA-reactive species of AAT examined by CIAE. Thus, the percentages of LCA-reactive species of AAT examined by CIAE can be used as a substitute for the amount of fucosylated sugar chain of AAT.}, pages = {11--14}, title = {Measurement of the Fucosylated Sugar Chains of Serum α_1-Antitrypsin : The Relationship between Reactivity with Lens Culinaris Agglutinin and HPLC Analysis of the Pyridylaminated Sugar Chains}, volume = {45}, year = {1997} }