@article{oai:niigata-u.repo.nii.ac.jp:00006407, author = {Nishimura, Atsushi and Fujita, Nobuhiro and Sakaguchi, Takeo and Aono, Takashi and Tsukada, Kazuhiro and Hatakeyama, Katsuyoshi}, issue = {2}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Jun}, note = {Portal venous blood flow (PVF) and systemic arterial pressure (SAP) were examined after dopamine (DA) injection into the portal or femoral vein in 66 percent hepatectomized rats. The portal injection of DA at 25 μg/kg/min evoked an increase in PVF without any change in SAP. PVF response due to portal DA injection tended to be dose dependent, and when portal venous resistance was defined as portal venous pressure/PVF, the resistance was reduced concomitant with an increase in PVF. The same dosage of DA injected into the femoral vein increased PVF with an increase in SAP. These results suggest that DA directly contributes to the PVF control under a hepatectomized condition, and that DA receptor in the portal vasculature is involved in this response.}, pages = {75--79}, title = {Portal Injection of Dopamine Directly Increases Portal Venous Blood Flow in 66 Percent Hepatectomized Rats}, volume = {45}, year = {1997} }