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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.45 No.4

Effects of Jejunoileal Transplantation on Myoelectrical Activity in the Rat Small Intestine

http://hdl.handle.net/10191/33135
http://hdl.handle.net/10191/33135
b7897da5-65a5-4db5-a797-0eec7df9803e
名前 / ファイル ライセンス アクション
45(4)_153-159.pdf 45(4)_153-159.pdf (1.1 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-08-25
タイトル
タイトル Effects of Jejunoileal Transplantation on Myoelectrical Activity in the Rat Small Intestine
タイトル
言語 en
タイトル Effects of Jejunoileal Transplantation on Myoelectrical Activity in the Rat Small Intestine
言語
言語 eng
キーワード
主題Scheme Other
主題 transplantation
キーワード
主題Scheme Other
主題 small intestine
キーワード
主題Scheme Other
主題 myoelectrical activity
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Okamoto, Haruhiko

× Okamoto, Haruhiko

WEKO 52668

Okamoto, Haruhiko

Search repository
Sakai, Yasuo

× Sakai, Yasuo

WEKO 52669

Sakai, Yasuo

Search repository
Sato, Kenji

× Sato, Kenji

WEKO 52670

Sato, Kenji

Search repository
Matsuo, Hitoshi

× Matsuo, Hitoshi

WEKO 52671

Matsuo, Hitoshi

Search repository
Hatakeyama, Katsuyoshi

× Hatakeyama, Katsuyoshi

WEKO 52672

Hatakeyama, Katsuyoshi

Search repository
Muto, Terukazu

× Muto, Terukazu

WEKO 52673

Muto, Terukazu

Search repository
抄録
内容記述タイプ Abstract
内容記述 Background: Clinically, many attempts at small intestinal transplantation in humans have been performed. Although little is known about the long term results on motor function of the transplanted small intestine, small intestinal motility should continue to be one of the most important issues in small intestinal transplantation. Study design: We investigated small intestinal motility 10 to 15 months after orthotopic small intestinal transplantation in rats. Six male Lewis rats underwent orthotopic jejunoileal transplantation. Intestinal myoelectric activity was recorded in the rats using Ag-AgCl bipolar electrodes. Six age-matched Lewis rats were also studied as controls. Results: The cycle length of migrating myoelectric complexes (MMCs) in the transplanted jejunum (T-J), recipient's jejunum (R-J), and jejunum of the control rat (C-J) groups were 16.2±3.8 min, 13.7±1.4 min, and 1l.1±0.3 min, respectively. In the C-J and T-J, a respective 98.1% and 96.5% of phase IIIs at the distal site occurred following the phase IIIs at the proximal site within 20% variation of the MMC period. However, between the R-J and T-J, only 31.0% of phase IIIs occurred within 20% variation of the MMC period. Coordination of the MMCs between the recipient and transplanted intestine did not occur at 10 to 15 months after the operation in the rat. During fasting, MMCs were clearly identified in the small intestine of both control and transplanted rats. Feeding interrupted the periodic activity, and irregular spike activity was observed along the entire small intestine, though conversion of the fasting to the fed pattern was delayed by about a minute in the graft intestine. The slow wave frequencies in the T-J, R-J, and C-J were 32.8±2.7 cpm, 36.3 ± 2.7 cpm and 36.3 ± 2.4 cpm, respectively. Conclusion: These results suggest that the motility of the transplanted small intestine is mostly preserved, however, temporal coordination of the MMCs across the anastomosis did not occur after transplantation.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 45, 号 4, p. 153-159, 発行日 1997-12
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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