{"created":"2021-03-01T06:10:16.343966+00:00","id":6369,"links":{},"metadata":{"_buckets":{"deposit":"dc1464ff-8da2-41e1-b696-f309c842fab6"},"_deposit":{"id":"6369","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6369"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006369","sets":["453:456","471:537:568:610"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"87","bibliographicPageStart":"81","bibliographicVolumeNumber":"46","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"This study aims to elucidate the relationship between arterial plasma potassium concentration ([K^+]_a) and ventilation, and evaluate the effect of hyperoxia on the ventilation- [K^+]_a relationship during incremental exercise testing in patients with chronic obstructive pulmonary disease (COPD). We studied 16 male patients with COPD. Using a bicycle ergometer, each patient started to exercise with a work load of 25W, which was increased in steps of 5W in one minute intervals until the symptom-limited endpoint. The same trial with oxygen inhalation was also performed in 6 out of 16 patients. During the exercise testing in room air (n=16), [K^+]_a increased from the baseline (3.82 ± 0.18 mEq / L) to 4.62±0.33 mEq/L (p<0.01). Once exercise stopped, [K^+]_a decreased rapidly. In all patients, the increase in minute ventilation volume(V^^・_E) was significantly correlated with the elavation of [K^+]_a (p<0.05). Ventilatory response to [K^+]_a (the slope of △V_E/△K^+) varied markedly among the patients (13.1 to 50.7 L/min/mEq/L), and was correlated with forced vital capacity (FVC) (P< 0.05). During the trial with oxygen inhalation (n=6), the mean slope of △V^^・_E/△K^+ was not depressed, compared with the room air run, which was 21.9±11.9 in the former and 25.4±13.1 L/min/mEq/L in the latter, respectively. These findings indicate that: 1) ventilation and [K^+]_ a were correlated during exercise; 2) the slope of ventilatory response to [K^+]_a differed markedly among the patients, and was correlated with FVC; and 3) hyperoxia did not significantly affect the ventilation[K^+]_a relationship. We conclude that, while [K^+]_a may play some role, certain unknown factors may also be involved in determining the degree of exercise hyperpnea in patients with COPD.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakajima, Toshiaki"}],"nameIdentifiers":[{"nameIdentifier":"52580","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohdaira, Tetsuro"}],"nameIdentifiers":[{"nameIdentifier":"52581","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoh, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"52582","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kurashige, Kazuyuki"}],"nameIdentifiers":[{"nameIdentifier":"52583","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yokota, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"52584","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Eiichi"}],"nameIdentifiers":[{"nameIdentifier":"52585","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kioi, Satoru"}],"nameIdentifiers":[{"nameIdentifier":"52586","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Arakawa, Masaaki"}],"nameIdentifiers":[{"nameIdentifier":"52587","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"46(3)_81-87.pdf","filesize":[{"value":"675.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"46(3)_81-87.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6369/files/46(3)_81-87.pdf"},"version_id":"08fb1191-6e1b-4ede-a95f-cb65f7842e0d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"arterial plasma potassium","subitem_subject_scheme":"Other"},{"subitem_subject":"exercise hyperpnea","subitem_subject_scheme":"Other"},{"subitem_subject":"hyperoxia","subitem_subject_scheme":"Other"},{"subitem_subject":"chronic obstructive pulmonary disease","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Relationship between Arterial Plasma Potassium Concentration and Ventilation during Exercise in Patients with Chronic Obstructive Pulmonary Disease","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Relationship between Arterial Plasma Potassium Concentration and Ventilation during Exercise in Patients with Chronic Obstructive Pulmonary Disease"},{"subitem_title":"The Relationship between Arterial Plasma Potassium Concentration and Ventilation during Exercise in Patients with Chronic Obstructive Pulmonary Disease","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","610"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-08-21"},"publish_date":"2015-08-21","publish_status":"0","recid":"6369","relation_version_is_last":true,"title":["The Relationship between Arterial Plasma Potassium Concentration and Ventilation during Exercise in Patients with Chronic Obstructive Pulmonary Disease"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:39:40.880119+00:00"}