@article{oai:niigata-u.repo.nii.ac.jp:00006348, author = {KOCH, HJ and RASCHKA, C}, issue = {3}, journal = {Acta medica et biologica, Acta medica et biologica}, month = {Sep}, note = {The diurnal courses of cortisol and differential blood count were determined at 08.00 H, 12.00 H, 16.00 H and 20.00 H in 14 healthy male subjects on two subsequent days. Data were analysed descriptively (mean/SD, linear regression) and sine wave models were fitted. Periodicity was investigated by means of autocorrelation. Relations between cortisol levels and hematology parameters were assessed using a crosscorrelation technique. Neutrophils correlated significantly with cortisol levels with a time lag of less than 4 hours. In contrast, the correlation of lymphocytes and cortisol was characterized by a time lag of 4 hours and that of eosinophils at a lag time of 4 hours In conclusion, hematology parameters and plasma cortisol appear to be closely related within a complex feedback network. The character of this interaction between hormonal and hematology parameters may have clinical relevance, and they may replace cortisol measurements if the correlations can be well established.}, pages = {107--114}, title = {Auto-and Crosscorrelation Analysis to Assess Diurnal Plasma Cortisol Levels and Routine Differential Blood Count Parameters}, volume = {47}, year = {1999} }