{"created":"2021-03-01T06:10:13.985810+00:00","id":6332,"links":{},"metadata":{"_buckets":{"deposit":"1b5bdb3f-92a1-4b6b-9036-d0bcf7661f2c"},"_deposit":{"id":"6332","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6332"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00006332","sets":["453:456","471:537:568:603"]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"74","bibliographicPageStart":"69","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Acta medica et biologica"},{"bibliographic_title":"Acta medica et biologica","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Inotropic and lusitropic reserves of failing hearts were investigated using a stepwise intravenous dobutamine loading test in patients with chronic heart failure. The forty-one patients enrolled in this study were classified into 4 groups according to the left ventricular end-systolic volume indices (LVESVI). The left ventricular size of Group 1 was within the normal range (LVESVI=37.0±3.5ml/m^2), and this group served as the control. LVESVI of Group 2 was mildly dilated (53.9±6.4ml/m^2), that of Group 3 was moderately dilated (77.3±4.7ml/m^2), and Group 4 was severely dilated (120.0±34.9ml/m^2). Left ventricular contractility and relaxation properties were estimated by left ventricular maximum positive dP/dt and minimum negative dP/dt. At the basal condition, both positive dP/dt and the absolute value of negative dP/dt were low in patients with chronic heart failure in accordance with LVESVI. Acceleration of positive dP/dt by dobutamine infusion was more attenuated in Group 4 than that of Group 1. However, responses of negative dP/dt were identical among the 4 groups. Thus, there was a dissociation between inotropic and lusitropic reserves of human failing hearts for β-adrenergic stimulation. These findings imply that a lusitropic reserve is preserved in the failing left ventricles in spite of an impairment to the inotropic reserve.","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Niigata University School of Medicine"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508361","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"05677734","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KODAMA, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"52394","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HANAWA, Haruo"}],"nameIdentifiers":[{"nameIdentifier":"52395","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KATO, Kiminori"}],"nameIdentifiers":[{"nameIdentifier":"52396","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"NAKAMURA, Yuichi"}],"nameIdentifiers":[{"nameIdentifier":"52397","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"OKURA, Yuji"}],"nameIdentifiers":[{"nameIdentifier":"52398","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HIRONO, Satoru"}],"nameIdentifiers":[{"nameIdentifier":"52399","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ITO, Masahiro"}],"nameIdentifiers":[{"nameIdentifier":"52400","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"FUSE, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"52401","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HOSONO, Hiroyuki"}],"nameIdentifiers":[{"nameIdentifier":"52402","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SAEKI, Makihiko"}],"nameIdentifiers":[{"nameIdentifier":"52403","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Minoru"}],"nameIdentifiers":[{"nameIdentifier":"52404","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KOYAMA, Sen"}],"nameIdentifiers":[{"nameIdentifier":"52405","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TSUDA, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"52406","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"WATANABE, Kenichi"}],"nameIdentifiers":[{"nameIdentifier":"52407","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"AIZAWA, Yoshifusa"}],"nameIdentifiers":[{"nameIdentifier":"52408","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-06"}],"displaytype":"detail","filename":"KJ00000007255.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000007255.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/6332/files/KJ00000007255.pdf"},"version_id":"6fe181cf-921e-4bce-b684-58a4bda522b8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"chronic heart failure","subitem_subject_scheme":"Other"},{"subitem_subject":"β-adrenoceptor","subitem_subject_scheme":"Other"},{"subitem_subject":"dobutamine","subitem_subject_scheme":"Other"},{"subitem_subject":"inotropic reserve","subitem_subject_scheme":"Other"},{"subitem_subject":"lusitropic reserve","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Preserved Lusitropic Reserve of the Left Ventricles in Spite of Impaired Inotropic Reserve in Patients with Chronic Heart Failure","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Preserved Lusitropic Reserve of the Left Ventricles in Spite of Impaired Inotropic Reserve in Patients with Chronic Heart Failure"},{"subitem_title":"Preserved Lusitropic Reserve of the Left Ventricles in Spite of Impaired Inotropic Reserve in Patients with Chronic Heart Failure","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","603"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-05-10"},"publish_date":"2007-05-10","publish_status":"0","recid":"6332","relation_version_is_last":true,"title":["Preserved Lusitropic Reserve of the Left Ventricles in Spite of Impaired Inotropic Reserve in Patients with Chronic Heart Failure"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T04:31:40.834221+00:00"}