@article{oai:niigata-u.repo.nii.ac.jp:00006328,
 author = {SUZUKI, Ayako and NAKAMURA, Takashi and OHNUKI, Toshio and HIRONO, Satoru and AIZAWA, Yoshifusa and WATANABE, Kenichi and NAGATOMO, Takafumi},
 issue = {2},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Jun},
 note = {In this study, we investigated changes in cardiac β-adrenoceptor densities (Bmax) and affinities (dissociation constant : Kd) by Scachard analysis using the radioligand binding assay method during the development of rat experimental autoimmune myocarditis (EAM). Rats at 11 weeks of age were subcutaneously injected in both foodpads with 0.2ml of antigen-adjuvant emulsion for the induction of EAM. A peak increase in Bmax values of cardiac muscles of EAM was observed at day 18 (active phase), followed by a tendency to decrease until day 214 after immunization. However, there were no changes in Kd values at any stage of EAM. Thus, the present study indicates that β-AR densities change according to the stages of EAM.},
 pages = {51--54},
 title = {Alterations in Cardiac β-Adrenoceptors During the Development of Rat Experimental Autoimmune Myocarditis},
 volume = {48},
 year = {2000}
}