@article{oai:niigata-u.repo.nii.ac.jp:00006219,
 author = {Higuchi, Kiyotaka and Nishikura, Ken and Ajioka, Yoichi and Watanabe, Gen},
 issue = {1},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Mar},
 note = {We studied the macroscopic features of differentiated-type gastric carcinomas to discern mucin phenotypes using 50 cases (54 lesions) of early gastric depressed type carcinomas, employing MUC5AC, MUC6, MUC2 and CD10 immunostains. We identified the G-phenotype (gastric phenotype) in 12 lesions, the gastrointestinal phenotype in 26 lesions, and the intestinal phenotype in 16 lesions. Carcinomas with the gastric phenotype revealed a significantly higher incidence of discolored surface (58.3%) than those with the intestinal phenotype (18.7%) (p<0.05). Carcinomas with the gastric phenotype also demonstrated a significantly higher incidence of non-wavy tumor margins (83.3%); those with the intestinal phenotype had only an 18.7% incidence of non-wavy tumor margins (p<0.01). No difference in the clarity of the marginal outline was found among the mucous phenotypes. The mucosal heights measured under a microscope revealed that the shallowest depressions among the nuclear-margin group were associated with gastric phenotype lesions.},
 pages = {9--20},
 title = {Macroscopic Findings and Mucous Phenotypes of Early Gastric Depressed Type Carcinomas},
 volume = {54},
 year = {2006}
}