@article{oai:niigata-u.repo.nii.ac.jp:00006191,
 author = {Numata, Osamu},
 issue = {4},
 journal = {Acta medica et biologica, Acta medica et biologica},
 month = {Jul},
 note = {Muscle stiffness or spasms and nuchal stiffness are usually associated with meningitis syndrome, but it is unknown whether or not such stiffness of the meningitis syndrome relates to a central nerve system dysfunction. The aim of this study was to evaluate excitability of the brain stem reticular formation in children with aseptic meningitis syndrome. The recovery cycle of the late response (R2) component of the blink reflex was studied in 12 children with aseptic meningitis syndrome and in 76 healthy control subjects. The R2 recovery was significantly enhanced at the interstimulus interval of 100 ms in children with aseptic meningitis syndrome in the acute stage, but it was not enhanced in the convalescent stage. This result suggests that the hyperexcitable R2 response transiently originate from reduced neural activity of the brain stem interneurons, and also explains such dysfunctions of the central inhibitory system can contribute concomitantly to muscle stiffness or nuchal stiffness in aseptic meningitis syndrome during acute stage., Postexercise proteinuria is a well-considered phenomenon in humans. The purpose of this study was to determine if low-intensity walking on underwater and land treadmills would induce urinary protein excretion in elderly people. Urinary protein concentration was measured on 10 healthy elderly women during the normal fasting state, both before and immediately after underwater and land treadmill walking at a speed of 2.0 Km/h for 15 min. As indicators for assessing physiological responses to the walking, we used heart rate, skin blood flow, muscle hardness, and subject judgment scores (ratings of thermal sensation, comfortable sensation, and perceived exertion). In the underwater treadmill walking, urinary protein concentration corrected for creatinine (CRE) concentration increased significantly (P = 0.013) after the walking (666 mg/gCRE) than before the walking (404 mg/gCRE), although none of the measured indicators of heart rate, skin blood flow, muscle hardness, or mean subjective judgment scores changed significantly after the walking. The increase in the corrected urinary protein concentration was attributed to the decreased urinary CRE concentration after the walking. In the land treadmill walking, however, none of the indicators significantly changed after the activity. Urinary protein excretion after underwater treadmill walking may reflect the greater resistance to movement encountered in water than on land. Although further studies applying different walking intensity are needed, the possibility that urinary protein can be used as an indicator to assess walking intensity in the elderly women could not be ruled out. Our results provide preliminary rationale for further studies on basic information for promoting walking for elderly women.},
 pages = {103--111},
 title = {Blink Reflex Excitability Recovery Curves in Children with Aseptic Meningitis Syndrome},
 volume = {55},
 year = {2012}
}