{"created":"2021-03-01T06:09:33.641923+00:00","id":5693,"links":{},"metadata":{"_buckets":{"deposit":"4be2c3b7-bd11-4d9e-8c3d-15d2b147a904"},"_deposit":{"id":"5693","owners":[],"pid":{"revision_id":0,"type":"depid","value":"5693"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00005693","sets":["453:455","471:561:562"]},"item_6_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"当施設単独における前立腺癌に対する1日2回高線量率組織内照射療法の経験と結果の検討"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03-23","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_6_date_granted_51":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2016-03-23"}]},"item_6_degree_grantor_49":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"新潟大学"}]}]},"item_6_degree_name_48":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"}]},"item_6_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We investigated the outcomes of treatment for patients with localized prostate cancer (PCa) treated with three-dimensional conformal radiation therapy (3D-CRT) followed by two-fraction high-dose-rate brachytherapy within a single day (2-fr.-HDR-BT/day) at a single institution. A total of 156 consecutive Asian males (median age, 67 years) were enrolled. To compare our findings with those of other studies, we analyzed our results using the D’Amico classification, assigning the patients to low-(n=5; 3.2%), intermediate-(n=36; 23.1%), and high-risk (n=115; 73.7%) groups (stage T3 PCa patients were classified as high-risk). One patient in the D’Amico low-risk group (20%), 13 intermediate-risk patients (36.1%) and 99 high-risk patients (86.1%) underwent androgen deprivation therapy. We administered a prescription dose of 39 Gy in 13 fractions of 3D-CRT combined with 18 Gy of HDR-BT in two 9-Gy fractions delivered within a single day. We did not distinguish between risk groups in determining the prescription dose. The median follow-up period was 38 months. Of the 156 patients, one died from primary disease and five died from other diseases. The 3-year overall survival (OS) rates were 100%, 100% and 93.7% and the 3-year ‘biochemical no evidence of disease (bNED)’ rates were 100%, 100% and 96.9% for the D’Amico low-, intermediate- and high-risk groups, respectively. No patient developed≥Grade 3 early toxicity. The Grade 3 late genitourinary toxicity rate was 2.6%, and no ≥Grade 3 late gastrointestinal toxicity occurred. The efficacy and safety of this study were satisfactory, and longer-term follow-up is necessary.","subitem_description_type":"Abstract"}]},"item_6_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"学位の種類: 博士（医学）. 報告番号: 甲第4108号. 学位記番号: 新大院博（医）甲第675号. 学位授与年月日: 平成28年3月23日","subitem_description_type":"Other"},{"subitem_description":"Journal of Radiation Research. First published online: March 16, 2016","subitem_description_type":"Other"}]},"item_6_description_53":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_description":"新大院博（医）甲第675号","subitem_description_type":"Other"}]},"item_6_dissertation_number_52":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"13101甲第4108号"}]},"item_6_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"50738","nameIdentifierScheme":"WEKO"}],"names":[{"name":"劉, 君陽"}]}]},"item_6_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟大学"}]},"item_6_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1093/jrr/rrw003","subitem_relation_type_select":"DOI"}}]},"item_6_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright(C) The Author 2016. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology."}]},"item_6_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"ETD"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Liu, Junyang"}],"nameIdentifiers":[{"nameIdentifier":"50737","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-05"}],"displaytype":"detail","filename":"h27nmk675.pdf","filesize":[{"value":"774.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://niigata-u.repo.nii.ac.jp/record/5693/files/h27nmk675.pdf"},"version_id":"d80a6f58-1d8a-462c-812a-bb205c1978f3"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-05"}],"displaytype":"detail","filename":"h27nmk675_a.pdf","filesize":[{"value":"577.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"要旨","url":"https://niigata-u.repo.nii.ac.jp/record/5693/files/h27nmk675_a.pdf"},"version_id":"3238a022-bddf-4c46-96c5-697d46119058"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"High-dose-rate","subitem_subject_scheme":"Other"},{"subitem_subject":"Brachytherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"HDR-BT","subitem_subject_scheme":"Other"},{"subitem_subject":"Radiotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Prostate cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Toxicity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"Two-Fraction High-Dose-Rate Brachytherapy within a Single Day Combined with External Beam Radiotherapy for Prostate Cancer : Single Institution Experience and Outcomes.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Two-Fraction High-Dose-Rate Brachytherapy within a Single Day Combined with External Beam Radiotherapy for Prostate Cancer : Single Institution Experience and Outcomes."},{"subitem_title":"Two-Fraction High-Dose-Rate Brachytherapy within a Single Day Combined with External Beam Radiotherapy for Prostate Cancer : Single Institution Experience and Outcomes.","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["455","562"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-05-19"},"publish_date":"2016-05-19","publish_status":"0","recid":"5693","relation_version_is_last":true,"title":["Two-Fraction High-Dose-Rate Brachytherapy within a Single Day Combined with External Beam Radiotherapy for Prostate Cancer : Single Institution Experience and Outcomes."],"weko_creator_id":"1","weko_shared_id":2},"updated":"2022-12-15T03:38:51.752694+00:00"}