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Methods: We studied 20 patients with localized prostate cancer who received IMRT between November 2010 and February 2012. After the initial setup, the pelvic bony structure-based setup and ExacTrac system were applied. After that, CBCT and a soft tissue-based setup were used. A shift in the isocenter between the ExacTrac-based and CBCT-based setup was recorded in the anterior-posterior (AP), superior-inferior (SI), and left-right (LR) axes. The shift was considered an inter-fractional prostate shift. Post-treatment CBCT was also taken once a week to measure the intra-fractional prostate shift, based on the coordinates of the isocenter between pre- and post-treatment CBCT. The planning target volume (PTV) margins were determined van Herk\u0027s method. We measured the elapsed time required for soft tissue matching and the entire treatment time using CBCT. Results: The means ± standard deviation (SD) of the inter- and intra-fractional shifts were 0.9 ± 2.8 mm and −0.30 ± 1.4 mm in the AP, 0.9 ± 2.2 mm and −0.1 ± 1.2 mm in the SI, and 0.1 ± 0.7mm in the LR. The PTV margins in the cases of bony structure-based and soft tissue-based setup were 7.3 mm and 2.7 mm in the AP, 5.8 mm and 2.3 mm in the SI, and 1.9 mm and 1.2 mm in the LR. Even though the median elapsed time using CBCT was expanded in 5.9 minutes, the PTV margins were significantly reduced. 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Superiority of a soft tissue-based setup using cone-beam computed tomography over a bony structure-based setup in intensity-modulated radiotherapy for prostate cancer
http://hdl.handle.net/10191/35553
http://hdl.handle.net/10191/355534ce1a347-5b45-4212-8d57-fe18dabf1282
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2015-12-14 | |||||
タイトル | ||||||
タイトル | Superiority of a soft tissue-based setup using cone-beam computed tomography over a bony structure-based setup in intensity-modulated radiotherapy for prostate cancer | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Superiority of a soft tissue-based setup using cone-beam computed tomography over a bony structure-based setup in intensity-modulated radiotherapy for prostate cancer | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | intensity-modulated radiotherapy (IMRT) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | prostate cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cone-beam computed tomography (CBCT) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | image-guided radiotherapy (IGRT) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | soft tissue-based setup | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | 前立腺癌強度変調放射線治療における骨照合法に対するコーンビームCTを用いた組織照合法の優位性 | |||||
著者 |
Sato, Hiraku
× Sato, Hiraku |
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著者別名 | ||||||
識別子 | 50646 | |||||
識別子Scheme | WEKO | |||||
姓名 | 佐藤, 啓 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: To test the superiority of a soft tissue-based setup using cone-beam computed tomography (CBCT) to a bony structure-based setup using the ExacTrac system in intensity-modulated radiotherapy (IMRT) for prostate cancer. Methods: We studied 20 patients with localized prostate cancer who received IMRT between November 2010 and February 2012. After the initial setup, the pelvic bony structure-based setup and ExacTrac system were applied. After that, CBCT and a soft tissue-based setup were used. A shift in the isocenter between the ExacTrac-based and CBCT-based setup was recorded in the anterior-posterior (AP), superior-inferior (SI), and left-right (LR) axes. The shift was considered an inter-fractional prostate shift. Post-treatment CBCT was also taken once a week to measure the intra-fractional prostate shift, based on the coordinates of the isocenter between pre- and post-treatment CBCT. The planning target volume (PTV) margins were determined van Herk's method. We measured the elapsed time required for soft tissue matching and the entire treatment time using CBCT. Results: The means ± standard deviation (SD) of the inter- and intra-fractional shifts were 0.9 ± 2.8 mm and −0.30 ± 1.4 mm in the AP, 0.9 ± 2.2 mm and −0.1 ± 1.2 mm in the SI, and 0.1 ± 0.7mm in the LR. The PTV margins in the cases of bony structure-based and soft tissue-based setup were 7.3 mm and 2.7 mm in the AP, 5.8 mm and 2.3 mm in the SI, and 1.9 mm and 1.2 mm in the LR. Even though the median elapsed time using CBCT was expanded in 5.9 minutes, the PTV margins were significantly reduced. Conclusions: We found the calculated PTV margins in the soft tissue-based setup using CBCT were small, and this arrangement was superior to the bony structure-based setup in prostate IMRT. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 学位の種類: 博士(医学). 報告番号: 甲第4061号. 学位記番号: 新大院博(医)甲第650号. 学位授与年月日: 平成27年9月24日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Applied Clinical Medical Physics. 2015, 16(5), 239-245. | |||||
書誌情報 | p. 1-29, 発行日 2015-09-24 | |||||
出版者 | ||||||
出版者 | 新潟大学 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1120/jacmp.v16i5.5448 | |||||
著者版フラグ | ||||||
値 | ETD | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 新潟大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2015-09-24 | |||||
学位授与番号 | ||||||
学位授与番号 | 13101甲第4061号 | |||||
学位記番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新大院博(医)甲第650号 |