@misc{oai:niigata-u.repo.nii.ac.jp:00005608,
 author = {Takeishi, Ryosuke},
 month = {Mar},
 note = {Pharyngeal electrical stimulation (PES) has been found to facilitate voluntary swallowing, This study investigated how PES contributes to modulation of swallowing function in 12 healthy humans. In the the involuntary swallowing test, distilled water was injected onto the pharynx at 0.1 mL/s and the onset latency of the first swallow was measured. In the the voluntary swallowing test, subjects swallowed their own saliva as quickly as possible for 30 s and the number of swallows was counted. Voluntary and involuntary swallowing was evaluated before (control), immediately after and every 10 min after 10-min PES (75% of tolerated sensation, 5 Hz and 1 ms pulse) for 60 minutes. Voluntary swallowing test during PES was also conducted before (control) and 60 min after 10-min PES. The onset latency in the involuntary swallowing test tended to decrease and the number of voluntary swallows tended to decrease immediately after 10-min PES. There was a negative correlation between the changes. The number of voluntary swallows with PES significantly increased 60 min after 10-min PES as compared with baseline. Repeat 10-min PES over 5 days significantly facilitated voluntary swallowing, with significant increases in the number of voluntary swallows. Involuntary swallowing function was not affected by PES. The results suggest that PES may have a long-term facilitatory effect on initiation of voluntary swallowing even in healthy humans but not on peripherally evoked swallowing. Daily repeat application of PES may also be useful in increasing the number of voluntary swallows. Physiological implications for the modulation and possibility of using the methods in dysphagic patients are discussed., 学位の種類: 博士（歯学）. 報告番号: 甲第4016号. 学位記番号: 新大院博（歯）甲第329号. 学位授与年月日: 平成27年3月23日, 新大院博（歯）甲第329号},
 title = {Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans},
 year = {2015}
}