{"created":"2021-03-01T06:08:12.033902+00:00","id":4402,"links":{},"metadata":{"_buckets":{"deposit":"8af4bc63-f1de-4d35-8c82-211f3dc35af9"},"_deposit":{"id":"4402","owners":[],"pid":{"revision_id":0,"type":"depid","value":"4402"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00004402","sets":["453:455","471:561:562"]},"item_6_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Magnetic Resonance Study on the Erythrocytes from Myotonic Dystrophy"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-03-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"37","bibliographicPageStart":"1","bibliographic_titles":[{}]}]},"item_6_date_granted_51":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"1992-03-03"}]},"item_6_degree_grantor_49":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"新潟大学"}]}]},"item_6_degree_name_48":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"}]},"item_6_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We have studied the water permeability through membranes, the function of the Na　pump, and glucose metabolism of erythrocytes of patients with myotonic muscular dystrophy (MyD) using 1H-, 23Na, and 13C-magnetic resonance spectroscopy (MRS). A significant decrease in water permeability was recognized in the MyD erythrocyte meinbrane, and impared Na pumping was suspected to be correlated with the former biochemical abnormalities in hand III protein of MyD erythrocyte membrane. Significant acrelation of glycolysis in erythrocyte for the first 160 minutes was also recognized in MyD however, the production of lactate showed no difference between MyD and controls. The increased glucose uptake in MyD may be compensatory to the diminished pumping mechanism, but further information, such as inorganic phosphate permeability and the activity of the rate-limiting enzyme of erythrocyte glycolysis is needed.","subitem_description_type":"Abstract"}]},"item_6_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"学位の種類: 博士（医学）. 報告番号: 乙第1234号. 学位記番号: 新大博（医）乙第1149号. 学位授与年月日: 平成4年3月3日","subitem_description_type":"Other"},{"subitem_description":"新潟医学会雑誌. 1992, 106(6), 563-572.","subitem_description_type":"Other"}]},"item_6_description_53":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_description":"新大博（医）乙第1149号","subitem_description_type":"Other"}]},"item_6_dissertation_number_52":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"13101B1234"}]},"item_6_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"48385","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kuwabara, Takeo"}]}]},"item_6_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟大学"}]},"item_6_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"ETD"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"桑原, 武夫"}],"nameIdentifiers":[{"nameIdentifier":"48384","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-05"}],"displaytype":"detail","filename":"000000251493.pdf","filesize":[{"value":"3.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://niigata-u.repo.nii.ac.jp/record/4402/files/000000251493.pdf"},"version_id":"ef346434-ae00-46bb-a6c1-1c84fdd83e29"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"MRS","subitem_subject_scheme":"Other"},{"subitem_subject":"myotonic dystrophy","subitem_subject_scheme":"Other"},{"subitem_subject":"erythrocyte","subitem_subject_scheme":"Other"},{"subitem_subject":"water permeability","subitem_subject_scheme":"Other"},{"subitem_subject":"Na pump","subitem_subject_scheme":"Other"},{"subitem_subject":"glycolysis","subitem_subject_scheme":"Other"},{"subitem_subject":"磁気共鳴スペクトロスコピー","subitem_subject_scheme":"Other"},{"subitem_subject":"筋緊張性ジストロフィー症","subitem_subject_scheme":"Other"},{"subitem_subject":"赤血球","subitem_subject_scheme":"Other"},{"subitem_subject":"水交換","subitem_subject_scheme":"Other"},{"subitem_subject":"ナトリウムポンプ","subitem_subject_scheme":"Other"},{"subitem_subject":"糖代謝","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"筋緊張性ジストロフィー症患者赤血球の磁気共鳴法による研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"筋緊張性ジストロフィー症患者赤血球の磁気共鳴法による研究"},{"subitem_title":"筋緊張性ジストロフィー症患者赤血球の磁気共鳴法による研究","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["455","562"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-10-08"},"publish_date":"2013-10-08","publish_status":"0","recid":"4402","relation_version_is_last":true,"title":["筋緊張性ジストロフィー症患者赤血球の磁気共鳴法による研究"],"weko_creator_id":"1","weko_shared_id":2},"updated":"2022-12-15T03:37:14.034301+00:00"}