{"created":"2021-03-01T06:08:11.779858+00:00","id":4398,"links":{},"metadata":{"_buckets":{"deposit":"a4380de2-5cd6-469e-ad21-023cbedc2efa"},"_deposit":{"id":"4398","owners":[],"pid":{"revision_id":0,"type":"depid","value":"4398"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00004398","sets":["453:455","471:561:562"]},"item_6_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"ラット結腸癌培養細胞株ACL-15の樹立とその転移能"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-12-18","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_6_date_granted_51":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"1991-12-18"}]},"item_6_degree_grantor_49":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"新潟大学"}]}]},"item_6_degree_name_48":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"}]},"item_6_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A new cultured cell line (ACL-15) was established from a transplantable rat colon cancer strain induced by 1,2-dimenthyl hydrazine (DMH). Histologically, the primary colonic tumor was a poorly differentiated adenocarcinoma; all transplanted tumor showed the same histologic features. The doubling time of the ACL-15 cell line population was 24h, and the saturation density was 5,6×10^5 cells/cm^2 in culture. The chromosome number and DNA content of the ACL-15 cells were near tetraploid. ACL-15 cells frequently metastasized to the liver and lungs in vivo. Thirty percent of those rats inoculated with ACL-15 cells into the subserosa of the cecum and all rats which received intrasplenic inoculations of ACL-15 cells developed hepatic metastases. All rats injected multiple pulmonary metastases. This newly established cell line. ACL-15, can serve for a model of metastatic colonic cancer.","subitem_description_type":"Abstract"}]},"item_6_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"学位の種類: 博士（医学）. 報告番号: 乙第1191号. 学位記番号: 新大博（医）乙第1108号. 学位授与年月日: 平成3年12月18日","subitem_description_type":"Other"},{"subitem_description":"Acta Medica et Boologica.75, ,39(2). 1991-06","subitem_description_type":"Other"}]},"item_6_description_53":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_description":"新大博（医）乙第1108号","subitem_description_type":"Other"}]},"item_6_dissertation_number_52":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"13101B1191"}]},"item_6_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"48377","nameIdentifierScheme":"WEKO"}],"names":[{"name":"鹿嶋, 雄治"}]}]},"item_6_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟大学"}]},"item_6_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"ETD"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kashima, Yuji"}],"nameIdentifiers":[{"nameIdentifier":"48376","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-05"}],"displaytype":"detail","filename":"000000251450.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://niigata-u.repo.nii.ac.jp/record/4398/files/000000251450.pdf"},"version_id":"52347130-daf6-4aa0-880e-f61550b7a0c7"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"The Establishment of a Rat Colon Cancer Cell Line,ACL-15,with an Analysis of Its Metastatic Properties","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Establishment of a Rat Colon Cancer Cell Line,ACL-15,with an Analysis of Its Metastatic Properties"},{"subitem_title":"The Establishment of a Rat Colon Cancer Cell Line,ACL-15,with an Analysis of Its Metastatic Properties","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["455","562"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-10-09"},"publish_date":"2013-10-09","publish_status":"0","recid":"4398","relation_version_is_last":true,"title":["The Establishment of a Rat Colon Cancer Cell Line,ACL-15,with an Analysis of Its Metastatic Properties"],"weko_creator_id":"1","weko_shared_id":2},"updated":"2022-12-15T03:37:17.490505+00:00"}