@article{oai:niigata-u.repo.nii.ac.jp:00003656, author = {池田, 圭介 and 真貝, 富夫 and 高橋, 義弘 and 山田, 好秋 and 河野, 正司}, issue = {1}, journal = {日本顎口腔機能学会雑誌, 日本顎口腔機能学会雑誌}, month = {Aug}, note = {The effect of afferent signals from the periodontal ligament and muscle spindles of jaw-closing muscles on adrenal medullary function is not known. We approached this matter through analysis of adrenal sympathetic nerve activity, trajectories of jaw movements, and EMG activity of the masseter muscle recorded simultaneously in anesthetized rats. Rhythmic jaw movements (RJM) were evoked by repetitive electrical stimulation of the cerebral cortex. There was no significant change in the adrenal nerve activity during RJM. When a 2 mm-thick wooden stick was placed between the opposing incisors during RJM, the activities of the masseter muscle and the adrenal nerve were facilitated. The facilitative response of the adrenal nerve returned to the pre-stimulus level after the wooden stick was withdrawn. After sectioning the bilateral maxillary and inferior alveolar nerves, the facilitative response to the masseteric activity due to application of the wooden stick became greatly reduced but no significant change was seen in the adrenal nerve activity. The masseteric activity increased while the jaw was stretched during RJM to increase the afferent signals from the muscle spindles;however, the adrenal nerve activity did not change signicicantly. Adrenal nerve activity was facilitated when pressure stimulation was applied manually to the upper incisors. The facilitative effect was much greater during repetitive stimulation to the teeth than that observed during continuous stimulation. These results indicate that afferent signals from the periodontal ligament are responsible for the facilitation of adrenal nerve activity., 歯根膜および閉口筋筋紡錘からの感覚情報が副腎髄質機能に及ぼす影響を調べる目的で,麻酔ラットを用いて副腎交感神経活動,下顎運動および咬筋筋電図を同時記録し解析を行った.大脳皮質の連続電気刺激によりリズミカルな下顎運動を誘発した.誘発されたリズミカルな下顎運動中,副腎交感神経活動に明らかな変化は認められなかった.リズミカルな下顎運動中に,上下切歯間に木片(厚さ2mm)を挿入し咬合させると,咬筋活動および副腎交感神経活動は増加した.木片を撤去すると,副腎交感神経活動は木片の咬合前のレベルまで戻った.あらかじめ上顎神経および下歯槽神経を両側性に切断した動物では,リズミカルな下顎運動中の木片咬合による咬筋活動の促通効果は減少し,副腎交感神経の活動には明らかな増加は認められなかった.リズミカルな下顎運動中に下顎を牽引することで筋紡錘感覚情報を増加させると,咬筋活動は増加したが,副腎交感神経活動には明らかな変化は認められなかった.また,上顎切歯に手動で圧刺激を行った際には副腎交感神経活動の増加がみられ,この効果は持続圧刺激よりも反復圧刺激の方が大きかった.以上の結果から,歯根膜感覚情報が副腎交感神経活動を増加させることが明らかになった.}, pages = {99--104}, title = {歯根膜感覚情報がラット副腎髄質機能に及ぼす影響}, volume = {4}, year = {1997} }