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Adipokines in patients with heart failure under rehabilitation
http://hdl.handle.net/10191/00051956
http://hdl.handle.net/10191/00051956a578793f-73d4-45f0-a5c7-9969b298dcb1
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本文 (504.8 kB)
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要旨 (455.2 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2020-11-12 | |||||
| タイトル | ||||||
| タイトル | Adipokines in patients with heart failure under rehabilitation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | adipokines | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | frailty | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | heart failure | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | leptin | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | osteoporosis | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
| 資源タイプ | thesis | |||||
| その他のタイトル | ||||||
| その他のタイトル | 心臓リハビリテーション実施心不全患者におけるアディポカイン | |||||
| 著者 |
Fujiki, Shinya
× Fujiki, Shinya |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 178219 | |||||
| 姓名 | 藤木, 伸也 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background Frailty is a multifactorial physiological syndrome most often associated with age but which has received increasing recognition as a component of chronic illnesses such as heart failure. Patients with heart failure are likely to be frail, irrespective of their age. Adipokine dysregulation, which is associated with frailty, occurs in patients with heart failure. In this study, we tested the hypothesis that adipokines are associated with skeletal muscle and bone mineral density that change lead to frailty in patients with heart failure. Methods Thirty-five patients with heart failure (age, 67 ± 14 years; 25 males; left ventricular ejection fraction, 45 ± 19%) were included. Serum adipokine levels, physical performance, and body composition were measured. Results Adiponectin and leptin were inversely correlated with grip strength. Adiponectin was inversely correlated with bone mineral density. Leptin was positively correlated with fat mass. Adipokines were not correlated with skeletal muscle mass. Conclusions Adipokines were associated with grip strength and bone mineral density in patients with heart failure. Adipokine dysregulation may play a role in the development of frailty in heart failure. | |||||
| 著者版フラグ | ||||||
| 値 | ETD | |||||
| 学位名 | ||||||
| 学位名 | 博士(医学) | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 新潟大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2020-09-23 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 13101甲第4795号 | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 新大院博(医)甲第965号 | |||||
