{"_buckets": {"deposit": "710efb69-dbd1-4f10-a875-7491193462db"}, "_deposit": {"id": "33708", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "33708"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00033708"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Animal Models of Heart Diseases, NASH and Atopic Dermatitis : From PhD. Thesis. Understanding the Past, Predicting the Future"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "259", "bibliographicPageStart": "251", "bibliographicVolumeNumber": "132", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c "}, {"bibliographic_title": "NIIGATA MEDICAL JOURNAL", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "My research projects in Niigata university of Pharmacy were mechanisms of human diseases including fatty acid metabolism, diabetic cardiomyopathy, atopic dermatitis, colitis and hepatitis et ct. Total twenty-one Students from abroad such as Bangladesh, India, Egypt, Syria, China, Indonesia et al. research mechanisms of many kinds of diseases. Three students from abroad graduated last year at the Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences. These students reported on treatments for heart disease, nonalcoholic steatohepatitis and atopic dermatitis and on underlying mechanisms. The titles of these reports are \u300cStudy of the role of cardiac 14-3-3 TJ protein in cardiac inflammation and adverse cardiac remodeling during heart failure in mice\u300d, \u300cNon-alcoholic steatohepatitis (NASH) : onset of mechanisms under diabetic background and treatment strategies\u300dand \u300cThe role of HMGBl and its cascade signaling pathway in atopic dermatitis\u300d. It can be concluded from these theses that oxidative stress and inflammation are some of the principal mechanisms underlying these diseases. Distinct disease phenotypes affect different organ systems, whereas overlapping disease phenotypes are more likely to be caused by two genes encoding proteins that interact within the same pathway.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "4553", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "WATANABE, Kenichi"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": " \u65b0\u6f5f\u533b\u5b66\u4f1a "}]}, "item_7_relation_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": " AN00182415 ", "subitem_relation_type_select": "NCID"}}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440 ", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u6e21\u8fba, \u8ce2\u4e00"}], "nameIdentifiers": [{"nameIdentifier": "60042", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "132(7)_251-259.pdf", "filesize": [{"value": "4.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 4400000.0, "url": {"url": "https://niigata-u.repo.nii.ac.jp/record/33708/files/132(7)_251-259.pdf"}, "version_id": "433c71cf-c357-45a5-82b5-d3079a85a57a"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Heart failure", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Diabetes", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Oxidative stress", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Endoplasmic reticulum stress", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "High mobility group box protein 1 (HMGBl)", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u52d5\u7269\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f, \u5fc3\u75be\u60a3\u30fb\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u708e\u30fb\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u7814\u7a76", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u52d5\u7269\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f, \u5fc3\u75be\u60a3\u30fb\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u708e\u30fb\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u7814\u7a76"}, {"subitem_title": "Animal Models of Heart Diseases, NASH and Atopic Dermatitis : From PhD. 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