{"created":"2021-03-01T06:39:50.426388+00:00","id":33413,"links":{},"metadata":{"_buckets":{"deposit":"72d84842-d2df-4fee-b1bf-edced6dc5201"},"_deposit":{"id":"33413","owners":[],"pid":{"revision_id":0,"type":"depid","value":"33413"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00033413","sets":["453:456","471:537:538:1931"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Perspectives of Therapeutic Strotegy for Lifestyle - related Disease (A Scientific Approach to Aging)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"166","bibliographicPageStart":"161","bibliographicVolumeNumber":"132","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"加齢が動脈硬化の独立したリスクファクターであることは，疫学的研究から証明されている．しかし，どのようなメカニズムによって心血管系が老化し，これらの変化を引き起こしているのかは，未解明な点が多い．そこで私は，老化研究を「細胞レベルの老化が個体老化の一部の形質，特に病的な形質を担う」という仮説に基づいて進めることにした．これらの老化シグナルが，重要な役割を担っており，動脈硬化や心不全，糖尿病の病態生理に深く関与していることを示唆するデータを得ているので紹介する．","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"176186","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Minamino, Tohru"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"南野, 徹"}],"nameIdentifiers":[{"nameIdentifier":"176185","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-19"}],"displaytype":"detail","filename":"132(5)_161-166.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"132(5)_161-166.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/33413/files/132(5)_161-166.pdf"},"version_id":"697d7821-562c-4f96-8864-1857643ead15"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"p53","subitem_subject_scheme":"Other"},{"subitem_subject":"cellular senescence","subitem_subject_scheme":"Other"},{"subitem_subject":"atherosclerosis","subitem_subject_scheme":"Other"},{"subitem_subject":"heart failure","subitem_subject_scheme":"Other"},{"subitem_subject":"diabetes","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"1 老化からみた生活習慣病診療の展望 (シンポジウム 老化を科学する，第727回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"1 老化からみた生活習慣病診療の展望 (シンポジウム 老化を科学する，第727回新潟医学会)"},{"subitem_title":"1 老化からみた生活習慣病診療の展望 (シンポジウム 老化を科学する，第727回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1931"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-11-16"},"publish_date":"2018-11-16","publish_status":"0","recid":"33413","relation_version_is_last":true,"title":["1 老化からみた生活習慣病診療の展望 (シンポジウム 老化を科学する，第727回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T04:02:32.956511+00:00"}